[Posterior reversible encephalopathy syndrome: about 2 cases related to the cyclosporine].

Ann Fr Anesth Reanim

Service d'anesthésie et de réanimation chirurgicale, hôpital G. et R.-Laennec, 44093 cedex 1, Nantes, France.

Published: May 2003

Following a pulmonary transplantation for cystic fibrosis, 2 patients exhibited a syndrome associating arterial hypertension, headache, visual trouble and generalized seizures. Cerebral magnetic resonance imaging revealed diffuse cortical and subcortical lesions predominantly in posterior regions. The exclusion of alternate diagnoses and the disappearance of the symptoms when the cyclosporine treatment was stopped confirmed the diagnosis of cyclosporine-related reversible posterior encephalopathy syndrome (PRES). Immediate appropriate management resulted in symptom disappearance and regression of radiological images.

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http://dx.doi.org/10.1016/s0750-7658(03)00097-2DOI Listing

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