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Plasma levels of matrix metalloproteinase 9 in patients undergoing off-pump coronary artery bypass grafting.
J Thorac Dis
April 2017
Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.
Background: Matrix metalloproteinase 9 (MMP9) has recently emerged as a risk predictor in patients with cardiovascular diseases. However, little is known about the significance of increased plasma MMP9 in patients with perioperative myocardial injury. We aimed to investigate the role of MMP9 in the occurrence of myocardial injury during off-pump coronary artery bypass grafting (OPCAB).
View Article and Find Full Text PDF[New Intracoronary Shunt Cannula in Off-pump Coronary Artery Bypass Grafting].
Kyobu Geka
November 2016
Department of Cardiovascular Surgery, Tomishiro Central Hospital, Tomishiro, Japan.
In off-pump coronary artery bypass grafting(OPCAB), a bloodless operative field has great influence on the quality of anastomosis. In addition, maintenance of distal coronary flow during anastomosis stabilizes hemodynamics. We introduced a new intracoronary shunt cannula, Mini Shunt Pro (MSP).
View Article and Find Full Text PDFPlasma levels of growth differentiation factor-15 are associated with myocardial injury in patients undergoing off-pump coronary artery bypass grafting.
Sci Rep
June 2016
Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Ruijin Er Road 197, Shanghai, 200025, P.R. China.
Growth differentiation factor-15 (GDF-15) has recently emerged as a risk predictor in patients with cardiovascular diseases. We therefore aimed to investigate the role of GDF-15 in the occurrence of cardiac injury during off-pump coronary artery bypass grafting (OPCAB). 55 consecutive patients with coronary artery diseases were recruited in this prospective, observational study.
View Article and Find Full Text PDFMinimised closed circuit coronary artery bypass grafting in the elderly is associated with lower levels of organ-specific biomarkers: a prospective randomised study.
Eur J Anaesthesiol
November 2013
From the Department of Cardio-Thoracic Surgery, Leiden University Medical Centre, Leiden (W-JPvB, RJK), Department of Clinical Chemistry and Haematological Laboratory, Gelre Hospital, Apeldoorn (WBG), Department of Cardio-Thoracic Surgery, Academic Medical Centre Amsterdam, Amsterdam (AHD), Department of Anaesthesiology, Intensive Care and Pain Management, St Antonius Hospital, Nieuwegein (EPvD), Department of Anaesthesiology Leiden University Medical Centre, Leiden (LPA), The Netherlands.
Background: Restrictive fluid management may protect organ function and improve postoperative outcome in elderly coronary artery bypass grafting (CABG) patients.
Objective: We assessed organ-specific biomarker release to study the contribution of a fluid restrictive closed circuit concept to organ protection in elderly CABG patients. Cardiac, respiratory and abdominal organ injury was measured during and following minimal fluid coronary artery bypass grafting (mCABG), off-pump coronary artery bypass (opCAB) surgery and conventional CABG with high volume prime and cold crystalloid cardioplegia (cCABG).
Effects of ulinastatin on coagulation in high-risk patients undergoing off-pump coronary artery bypass graft surgery.
Korean J Anesthesiol
February 2013
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea.
Background: Both systemic inflammatory reaction and regional myocardial ischemia/reperfusion injury may elicit hypercoagulability after off-pump coronary artery bypass grafting (OPCAB). We investigated the influence of ulinastatin, which suppresses the activity of polymorphonuclear leukocyte elastase and production of pro-inflammatory cytokines, on coagulation in patients with elevated high-sensitivity C-reactive protein (hsCRP) undergoing OPCAB.
Methods: Fifty patients whose preoperative hsCRP > 3.
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