Hematology and blood biochemistry in infant baboons (Papio hamadryas).

J Med Primatol

Department of Genetics, Department of Laboratory and Animal Medicine, Southwest Foundation for Biomedical Research, San Antonio, TX, 78245-0549, USA.

Published: June 2003

AI Article Synopsis

  • The study analyzed hematologic and clinical chemistry measures in 110 infant baboons (both sexes and hybrids) to fill a gap in reference standards since existing norms have only addressed adults.
  • The results revealed that while some hematology reference ranges for infants are similar to adults, they are generally wider, and blood biochemistry reference ranges show significant differences, suggesting adult ranges may not be suitable for infants.
  • Age was found to be a major factor affecting these measures, explaining over 10% of the variance, while sex and subspecies had minimal influence.

Article Abstract

Although published normative reference standards for hematologic and clinical chemistry measures are available for adult baboons, their applicability to infants has not been addressed. We analyzed these measures in 110 infant baboons (55 females and 55 males) from a large breeding colony at the Southwest Regional Primate Research Center in San Antonio, Texas. The sample consists of olive baboons and olive/yellow baboon hybrids, 1 week to 12 months of age. We produced cross-sectional reference values and examined the effects of age, sex, and subspecies on these variables. Hematology reference ranges for infant baboons are similar to, but wider than, those for adults. Reference ranges for blood biochemistry measures are generally more dissimilar to adults, indicating that for many variables, reference ranges for adult baboons are not adequate for infants. Although sex and subspecies differences are rare, age accounts for more than 10% of the variance in many of the variables.

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Source
http://dx.doi.org/10.1034/j.1600-0684.2003.00017.xDOI Listing

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