There was studied in spleen organotypic tissue culture the effect of vilon on the development of of proliferative activity in central and peripheral fields of explants of rats of various age: 3 days, 3 weeks and 2 years old. Vilon stimulated cell proliferation both in young and old rats, in spite of all there are reciprocal relations of this process in central and peripheral fields in the spleen organotypic culture of rats of various age.

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