AI Article Synopsis
- A study compared 785 patients who received no thromboprophylaxis with 957 patients treated with 6 weeks of low-dose warfarin after surgery.
- The control group had a lower total complication rate of 2.2%, whereas the warfarin group experienced a higher rate of 4.7% complications.
- Notably, both groups had zero deaths from thromboembolic disease, but the warfarin group had a higher infection rate and one death due to gastrointestinal bleeding.
Article Abstract
A cohort of 785 patients treated without any form of thromboprophylaxis was compared with an identical group of 957 patients treated with 6 weeks of low-dose warfarin. All complications seen within 90 days of surgery were recorded. The control group had a total complication rate of 2.2%, with a death rate from thromboembolic disease of 0.0% and a total death rate of 0.2%. The warfarin group had a total complication rate of 4.7%, with a death rate from thromboembolic disease of 0.0% and a total death rate of 0.1%. Both deaths in the control group were from cardiac disease, while the death in the warfarin group was due to a massive gastrointestinal bleeding. The warfarin group had twice the infection rate of the control group.
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| http://dx.doi.org/10.1016/s0883-5403(03)00071-8 | DOI Listing |
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