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Acute zoster-associated pain develops in most patients with herpes zoster. Nonopioid analgesics are usually used to treat acute zoster-associated pain but are frequently ineffective. We administered intravenous fosphenytoin, the prodrug of phenytoin, to patients with acute zoster-associated pain to examine its analgesic efficacy and safety.
View Article and Find Full Text PDFClinical and Laboratory Diagnosis of Exanthems Among Japanese Children Younger Than 6 Years Old in the Post-Measles-Rubella Vaccine Era.
Pediatr Infect Dis J
February 2024
Division of Infectious Diseases, Department of Medical Subspecialties.
Article Synopsis
- Exanthems are a frequent reason for pediatric emergency visits, particularly in children under 6, but there’s limited data post-vaccination for measles and rubella.
- A study in Japan from August 2019 to March 2020 classified the causes of exanthems in young children, using both clinical diagnosis and PCR tests for specific pathogens.
- Results showed that 54% of diagnosed cases were noninfectious or infectious diseases, with notable pathogens identified through PCR, making viral infections the most common underlying causes.
Live vaccines following intravenous immunoglobulin for Kawasaki disease: Are we vaccinating appropriately?
J Paediatr Child Health
November 2023
Infection and Immunity Theme, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
Aim: Australian and New Zealand guidelines recommend that live vaccines be postponed for 11 months after treatment of Kawasaki disease (KD) with intravenous immunoglobulin (IVIG). We aimed to describe patterns of live-vaccine administration after KD treatment, focusing on the measles-mumps-rubella/measles-mumps-rubella-varicella (MMR/MMRV) vaccines, and to compare real-world practice with current recommendations.
Methods: We combined data from inpatient Electronic Health Records and the Australian Immunisation Register for all children who received IVIG for the treatment of KD under the age of 5 years at two Australian tertiary children's hospitals over a 12-year period.
[Skin and SARS-CoV-2 in pediatrics].
Rev Alerg Mex
May 2022
Fundación Hospital Universitario Santa Fe de Bogotá, Departamento de Pediatría, Bogotá, Colombia.
The clinical presentation, disease course, and outcome of SARS-CoV-2 infection in pediatrics differ from the presentation in adults. In a review by Hoang et al., the prevalence of dermatological manifestations was estimated in 0.
View Article and Find Full Text PDFThe impact of patient skin colour on diagnostic ability and confidence of medical students.
Adv Health Sci Educ Theory Pract
October 2023
Imperial College School of Medicine, Imperial College London, London, United Kingdom.
Previous literature has explored unconscious racial biases in clinical education and medicine, finding that people with darker skin tones can be underrepresented in learning resources and managed differently in a clinical setting. This study aimed to examine whether patient skin colour can affect the diagnostic ability and confidence of medical students, and their cognitive reasoning processes. We presented students with 12 different clinical presentations on both white skin (WS) and non-white skin (NWS).
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