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Green Processing of : Antioxidant Concentration and Caffeine Reduction Using Encapsulation by Supercritical Antisolvent Process.
Molecules
November 2024
Departamento de Química, Universidad Técnica Particular de Loja, Loja 1101608, Ecuador.
This study investigated the valorization of leaves by producing a low-caffeine, antioxidant-rich product through the supercritical antisolvent extraction (SAE) process. The objective was to concentrate the antioxidants while selectively reducing the caffeine. The SAE treatments were conducted using an ethanolic extract of guayusa leaves under varying pressure (80 bar-150 bar) and temperature (35-45 °C) conditions to improve the recovery of chlorogenic acid (CGA) and caffeine fractionation.
View Article and Find Full Text PDFMetabolomic profiling of and grown Nilgiris tea reveals unique signatures for breeding decaffeinated varieties.
Nat Prod Res
October 2024
Department of Agriculture Entomology, Tamil Nadu Agricultural University, Coimbatore, India.
This study was begun by establishing an culture in UPASI 9, a Nilgiris tea clone () by optimising various factors. Anatomical studies demonstrated that use of lower carbendazim concentration for sterilisation (0.2%) produced viable and healthy explants for callus initiation.
View Article and Find Full Text PDFAcute Effects of Coffee Consumption on Blood Pressure and Endothelial Function in Individuals with Hypertension on Antihypertensive Drug Treatment: A Randomized Crossover Trial.
High Blood Press Cardiovasc Prev
January 2024
Department of Applied Nutrition, Nutrition Institute, State University of Rio de Janeiro, Ave. São Francisco Xavier, 524, Maracanã, Rio de Janeiro, RJ, Brazil.
Introduction: Coffee is a complex brew that contains several bioactive compounds and some of them can influence blood pressure (BP) and endothelial function (EF), such as caffeine and chlorogenic acids (CGAs).
Aim: This study aimed to evaluate the acute effects of coffee on BP and EF in individuals with hypertension on drug treatment who were habitual coffee consumers.
Methods: This randomized crossover trial assigned 16 adults with hypertension to receive three test beverages one week apart: caffeinated coffee (CC; 135 mg caffeine, 61 mg CGAs), decaffeinated coffee (DC; 5 mg caffeine, 68 mg CGAs), and water.
Suppression of Neuroinflammation by Coffee Component Pyrocatechol via Inhibition of NF-κB in Microglia.
Int J Mol Sci
December 2023
Division of Hygienic Chemistry, Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku 105-8512, Tokyo, Japan.
According to numerous studies, it has been epidemiologically suggested that habitual coffee intake seems to prevent the onset of neurodegenerative diseases. In this study, we hypothesized that coffee consumption suppresses neuroinflammation, which is closely related to the development of neurodegenerative diseases. Using microglial BV-2 cells, we first found that the inflammatory responses induced by lipopolysaccharide (LPS) stimulation was diminished by both coffee and decaffeinated coffee through the inhibition of an inflammation-related transcription factor, nuclear factor-κB (NF-κB).
View Article and Find Full Text PDFEffect of Caffeine on Colonic Manometry in Children.
J Pediatr Gastroenterol Nutr
January 2023
From the Orlando Health Arnold Palmer Hospital for Children, Orlando, FL.
Objectives: Coffee and caffeinated products have been widely consumed for many centuries. Previous adult studies have suggested that both coffee and decaffeinated beverages induce colonic motility. However, no study has been conducted in pediatrics, and the role of caffeine alone in pediatric colonic motility needs to be explored.
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