Objective: To analyze the neurophysiological characteristics of infants and young children with auditory neuropathy (AN) and explore their clinical significance.
Methods: Audiological measurements (acoustic immittance, EOAEs, ABR, CM, MLR and ERP) and peripheral neurological tests were conducted and evaluated in 13 infants and young children with AN. 6 AN patients received CT scan and/or MRI examination.
Results: All patients had type "A" tympanogram and normal CM. Normal EOAEs were elicited in 12 patients. 8 cases had normal MLR recording and 6 cases had normal ERP (P(300) and MMN). Peripheral neurological tests and CT and/or MRI showed normal results.
Conclusion: The diagnosis of AN in infants and young children should focus on analyzing their neurophysiological characteristics. Combined use of EOAEs, ABR and CM was recommended for hearing screening on newborns with high risk factors.
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