A total of 1,345 Ixodes persulcatus ticks collected from northeastern China were investigated for the presence of Anaplasma phagocytophila and Borrelia burgdorferi by a nested polymerase chain reaction (PCR). Sixty-two (4.6%) ticks were positive for A. phagocytophila and 454 (33.8%) were positive for B. burgdorferi. Seven (0.5%) were coinfected with both agents. Sequence analysis of 919-basepair PCR amplicons revealed three types of A. phagocytophila. Type 1 was identical to the published sequences of A. phagocytophilas responsible for human granulocytic ehrlichiosis (HGE). The other two variants differed from the HGE agent sequence at one and four positions, respectively. These findings imply that infection with A. phagocytophila poses a potential health threat to both humans and animals in northeastern China, and that ehrlichiosis should be considered in the differential diagnosis of febrile patients with a history of tick bite, particularly when clinical manifestations are atypical for Lyme disease.
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http://dx.doi.org/10.4269/ajtmh.2003.68.547 | DOI Listing |
Sci Rep
January 2025
School of Spatial Planning and Design, Hangzhou City University, Hangzhou, 310015, China.
Analysis of the spatiotemporal trends of urban scale and urban vitality on ecosystem services balance provides an essential basis for regional sustainable development. This study employs the Spatial Durbin Model (SDM), Spatial Autoregressive Model (SAR), and Geographically and Temporally Weighted Regression (GTWR) to effectively capture spatiotemporal associations between urban scale, urban vitality, and ecosystem services supply-demand balance, providing a detailed view of regional variations. The integrated framework combines spatiotemporal analysis, predictive scenario simulation, and importance-performance analysis to quantify and strategize urban impacts on ESs.
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January 2025
School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, 300072, China.
Yeast sex-hormone whole-cell biosensors are analytical tools characterized by long-time storage and low production cost. We engineered compact β-estradiol biosensors in S. cerevisiae cells by leveraging short (20-nt long) operators bound by the fusion protein LexA-ER-VP64-where ER is the human estrogen receptor and VP64 a strong viral activation domain.
View Article and Find Full Text PDFJ Phys Chem A
January 2025
Liaoning Key Laboratory of Manufacturing System and Logistics Optimization, Shenyang 110819, China.
Artificial intelligence technology has introduced a new research paradigm into the fields of quantum chemistry and materials science, leading to numerous studies that utilize machine learning methods to predict molecular properties. We contend that an exemplary deep learning model should not only achieve high-precision predictions of molecular properties but also incorporate guidance from physical mechanisms. Here, we propose a framework for predicting molecular properties based on data-driven electron density images, referred to as D3-ImgNet.
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January 2025
Department of Pathology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325035, China.
Cervical cancer is one of the deadliest cancers that pose a significant threat to women's health. Early detection and treatment are commonly used methods to prevent cervical cancer. The use of pathological image analysis techniques for the automatic interpretation of cervical cells in pathological slides is a prominent area of research in the field of digital medicine.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Corrosion and Protection Center, Northeastern University, Shenyang 110819, PR China.
The slippery liquid-infused porous surfaces (SLIPS) have recently attracted significant interest in marine antifouling and corrosion protection. Nevertheless, the insufficient durability and corrosion resistance of SLIPS considerably affect their application potential. In this work, a preparation strategy for ultradurable slippery organic coating was proposed to combat biofouling and corrosion.
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