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Eisenmenger syndrome during pregnancy: A true anesthetic challenge.
Med J Armed Forces India
December 2024
Professor & Senior Advisor, (Anaesthesia & Critical Care), Command Hospital (Eastern Command), Kolkata, West Bengal, India.
Eisenmenger syndrome (ES) is a rare congenital heart disease (CHD) that occurs in persons with large intracardiac anatomical defects which may go undetected for many years, consequently results in reduced life expectancies and high mortality in the third and fourth decade of life. Pregnancy in patients with CHD and pulmonary arterial hypertension (PAH) is presaged with challenges, and perioperative management of such cases remains a topic of debate. Our case had both, atypical presentation, not diagnosed until her third trimester of third pregnancy and a quick progression to a severe stage with PAH and CorPulmonale.
View Article and Find Full Text PDFLung transplantation for diffuse pulmonary arteriovenous malformations associated with juvenile polyposis-hereditary hemorrhagic telangiectasia overlap syndrome: a case report.
Gen Thorac Cardiovasc Surg Cases
December 2024
Department of Thoracic Surgery, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan.
Background: Lung transplantation is a viable lifesaving option for patients with diffuse pulmonary arteriovenous malformations (AVMs). We present a case of diffuse pulmonary AVMs associated with juvenile polyposis and hereditary hemorrhagic telangiectasia (JP-HHT) that was successfully managed by lung transplantation.
Case Presentation: A 19-year-old woman developed severe hypoxemia due to pulmonary AVMs diagnosed at 4 years of age.
Polycythemia vera with acute coronary syndrome and bleeding as initial presentation: A case report and literature review.
Radiol Case Rep
February 2025
Department of Hematology and Oncology, The Brooklyn Hospital Center, New York, NY, USA.
Polycythemia vera (PV) is a chronic myeloproliferative disorder characterized by increased red blood cell mass, leading to a heightened risk for thrombosis and hemorrhage. While thrombotic complications such as stroke, deep vein thrombosis, and pulmonary embolism are commonly associated with PV, coronary artery syndromes, as the initial presentation, are rare. Here, we present the case of a 73-year-old male who presented with severe chest pain and was diagnosed with non-ST-elevation myocardial infarction (NSTEMI).
View Article and Find Full Text PDFHomozygous Delta-Beta Thalassaemia With Alpha Thalassaemia and Erythrocytosis- a Rare Case Report.
Br J Biomed Sci
December 2024
Department of Hematology, Sandwell and West, Birmingham Hospitals National Health Service Trust, West Bromwich, United Kingdom.
In this report, we describe a case of homozygous delta-beta (δβ) thalassaemia, a rare genetic disorder characterized by severe deficiency in delta (δ) and beta (β)-globin chain production, leading to ineffective erythropoiesis and chronic haemolytic anaemia. The patient, a 26-year-old female with δβ-thalassaemia, experienced a miscarriage. High-performance liquid chromatography revealed 89.
View Article and Find Full Text PDFIncreased Risk of Persistent Pulmonary Hypertension of the Newborn in Twin Anaemia Polycythaemia Sequence Donors.
Fetal Diagn Ther
November 2024
Division of Fetal Therapy, Department of Obstetrics, Leiden University Medical Center, Leiden, The Netherlands.
Article Synopsis
- * Among 100 TAPS pregnancies, 32% experienced respiratory distress syndrome (RDS), 13% had bronchopulmonary dysplasia (BPD), and 7% had persistent pulmonary hypertension of the newborn (PPHN), with donors showing a higher incidence of PPHN.
- * The findings indicated that lower gestational age and severe fetal anaemia are significant risk factors for PPHN in TAPS twins, highlighting the need for specialized medical care during birth to manage potential complications.
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