It is widely accepted that patients with frontal lesions have problems inhibiting automatic response tendencies. Whereas inhibition deficits of overlearned responses have been extensively investigated using interference tasks like the Stroop task (J. R. Stroop, 1935), it is controversial whether patients with frontal brain lesions also have problems inhibiting imitative responses. Using an interference paradigm, the present study investigated imitative response tendencies in patients with frontal lesions. In addition, it tested whether patients deficient in the inhibition of imitative responses correspondingly have problems inhibiting overlearned responses. It was found that the group with frontal lesions displayed significantly stronger imitative response tendencies than the group with nonfrontal lesions. Furthermore, it was shown that the inhibition of imitative responses is functionally unrelated to Stroop interference.
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http://dx.doi.org/10.1037/0894-4105.17.2.265 | DOI Listing |
J Plast Surg Hand Surg
January 2025
Department of Plastic and Reconstructive Surgery, Skåne University Hospital, Malmö, Sweden.
Introduction: Health-related quality of life (HR-QoL) outcomes following maxillary reconstruction with the scapular osseous free flap (SOFF) are lacking. Material and Methods: To determine these outcomes, a study of patients who completed maxillary reconstruction with flap survival of the SOFF between 2016 and 2023 was conducted, using Face-Q Head and Neck Cancer Module (FACE-Q).
Results: Eligible patients had at least six months of follow-up.
Front Immunol
January 2025
Department of Dermatology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, United States.
Autoimmune diseases (AID) are defined by immune dysregulation characterized by specific humoral and/or cell mediated responses directed against the body's own tissues. Cytokines in particular play a pivotal role in the pathogenesis of AID, with proinflammatory cytokines contributing to the initiation and propagation of autoimmune inflammation, whereas anti-inflammatory cytokines facilitate regression of inflammation and recovery from acute phases of the disease. Parallel work by our group evaluating a comprehensive set of pro- and anti-inflammatory serum cytokines in Pemphigus vulgaris (PV) as well as Alopecia areata (AA) uncovered a similar pattern of inheritance specific immune dysregulation in these two distinct autoimmune skin diseases.
View Article and Find Full Text PDFHamostaseologie
January 2025
Center for Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany.
Congenital platelet disorders are rare and targeted treatment is usually not possible. Inherited platelet function disorders (iPFDs) can affect surface receptors and multiple platelet responses such as defects of platelet granules, signal transduction, and procoagulant activity. If iPFDs are also associated with a reduced platelet count (thrombocytopenia), it is not uncommon to be misdiagnosed as immune thrombocytopenia.
View Article and Find Full Text PDFPerspect Clin Res
August 2024
Department of Nephrology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.
Background: Pharmacotherapy of chronic kidney disease (CKD) consists of prescribing myriad of drugs such as antihypertensives, antidiabetics, and phosphate binders to delay disease progression and control the comorbidities, resulting in inherent variability in prescriptions. In addition, tendency to self-medicate may further aggravate the condition. Hence, the present study was planned to assess self-medication practices and variability in prescription patterns in CKD patients.
View Article and Find Full Text PDFSci Rep
January 2025
Annenberg School for Communication, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Decades of research hold that empathy is a multifaceted construct. A related challenge in empathy research is to describe how each subcomponent of empathy uniquely contributes to social outcomes. Here, we examined distinct mechanisms through which different components of empathy-Empathic Concern, Perspective Taking, and Personal Distress-may relate to prosociality.
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