AI Article Synopsis

  • A study analyzed the mortality rates of patients suspected of having Crimean-Congo hemorrhagic fever (CCHF) based on whether they received treatment with oral ribavirin.
  • Of the patients treated with ribavirin, 69.8% of those suspected of having CCHF survived, while 88.9% of confirmed CCHF patients survived.
  • The treatment showed an efficacy of 80% for confirmed CCHF cases, but only 34% for suspected cases, suggesting ribavirin is effective for treating the hemorrhagic form of CCHF despite some study limitations.

Article Abstract

We compared the mortality rate among patients suspected of having Crimean-Congo hemorrhagic fever (CCHF) who received treatment with oral ribavirin and those who did not. Ninety-seven (69.8%) of 139 treated patients suspected of having CCHF survived, and 61 (88.9%) of 69 treated patients with confirmed CCHF survived. The efficacy of oral ribavirin was 80% among patients with confirmed CCHF and 34% among patients suspected of having CCHF. Considering the limitations of observational studies, we conclude that oral ribavirin is an effective treatment for the hemorrhagic form of CCHF.

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http://dx.doi.org/10.1086/375058DOI Listing

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