AI Article Synopsis
- A study examined 439 patients, including 184 adults and 255 children, suffering from herpetic keratitis and other eye conditions like uveitis and chorioretinitis.
- The researchers identified reactivated HSV-infection by detecting antibodies to viral antigens in the blood using immune enzyme analysis (IEA).
- The test revealed active HSV infection in 16-39% of patients with non-herpetic ocular diseases, indicating that reactivated HSV can either cause or worsen existing eye conditions and lead to postoperative complications.
Article Abstract
A total of 439 patients (adults--184, children--255) with herpetic keratitis as well as with uveitis and choriorenitis of different geneses and localizations were examined. An aggravation of HSV-infection was determined by detecting, in the blood), anti-bodies to the unstructured early viral antigens by using the immune enzyme analysis (IEA). The efficiency of the test was demonstrated during the examination of patients with different ophthalmic pathologies. An active infection was detected in 16-39% of patients with various ocular diseases of non-herpetic etiology. The pathogenetic value of reactivated HSV infection is diverse: it can function as an etiological or trigger factor and it can aggravate the main disease through causing, postoperatively, complications.
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