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Ecstasy, molly, MDMA: What health practitioners need to know about this common recreational drug.
Dis Mon
January 2025
NYU Grossman School of Medicine, Department of Population Health, New York, NY, USA.
3,4-methylenedioxymethamphetamine (MDMA; commonly referred to as "ecstasy" or "molly") is a substituted amphetamine drug that is used recreationally for its acute psychoactive effects, including euphoria and increased energy, as well as prosocial effects such as increased empathy and feelings of closeness with others. Acute adverse effects can include hyperthermia, dehydration, bruxism, and diaphoresis. Post-intoxication phenomena may include insomnia, anhedonia, anxiety, depression, and memory impairment, which can persist for days following drug cessation.
View Article and Find Full Text PDFEvaluating utility of allergy testing in management of nasal obstruction following inferior turbinate reduction.
Int J Pediatr Otorhinolaryngol
January 2025
Department of Otolaryngology, Nationwide Children's Hospital, Columbus, OH, USA; Department of Otolaryngology, The Ohio State University Medical Center, Columbus, OH, USA. Electronic address:
Article Synopsis
- Allergic rhinitis (AR) is a prevalent chronic condition in children, often leading to nasal obstruction caused by inferior turbinate hypertrophy (ITH), which may require inferior turbinate reduction (ITR) surgery.
- The study reviewed data from 297 pediatric patients who underwent ITR in 2015, finding that 20.9% experienced recurrent nasal obstruction and 5.4% needed revision surgery afterward.
- Allergy testing was performed on about 37.7% of the patients, revealing no significant differences in recurrence or revision rates between those with positive and negative allergy test results.
Association between iron deficiency anemia and severe maternal morbidity: A retrospective cohort study.
Ann Epidemiol
December 2024
Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, United States. Electronic address:
Purpose: We examined the association between iron deficiency anemia (IDA) and severe maternal morbidity (SMM) during delivery and up to 1-year postpartum.
Methods: In a retrospective cohort study across 3 states, we computed adjusted relative risks (aRR) for SMM comparing individuals with IDA versus those without, using modified Poisson regression models.
Results: Among 2459,106 individuals, 10.
Lifestyle intervention improves cognition and quality of life in persons with early Multiple Sclerosis.
Mult Scler Relat Disord
November 2024
Pacific Brain Health Center, 1301 20th St., Santa Monica, California, 90404, United States; Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, USA. Electronic address:
Background: Lifestyle changes have been demonstrated to impact pathophysiology in Multiple Sclerosis (MS). Various diet and exercise protocols have been reported to improve symptoms and function in persons with MS. Evidence is accumulating that interventions as early as possible in the disease course are warranted.
View Article and Find Full Text PDFHealth Utility Values Among Patients With Diabetic Retinopathy, Wet Age-Related Macular Degeneration, and Cataract in Thailand: A Multicenter Survey Using Time Trade-Off, EQ-5D-5L, and Health Utility Index 3.
Value Health Reg Issues
November 2024
Department of Ophthalmology, Center of Excellence in Retina, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand. Electronic address:
Objectives: This study aimed to establish normative health utility data in Thai patients with diabetic retinopathy, wet age-related macular degeneration, and cataract; evaluate the sensitivity of different utility instruments to visual impairment; explore the relationship among these health utility values with the vision-specific quality of life (QoL); and assess the association of baseline characteristics and visual acuity level with health utility values and vision-specific QoL.
Methods: This multicenter cross-sectional survey included 309 patients from tertiary eye centers. We used health utility instruments (time trade-off [TTO], EuroQol five-dimension [EQ-5D-5L], and Health Utility Index 3 [HUI3]) and vision-specific QoL instrument (National Eye Institute Visual Function Questionnaire) for face-to-face interviews.
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