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http://dx.doi.org/10.1001/archsurg.138.6.672 | DOI Listing |
J Formos Med Assoc
March 2025
Department of Medical Oncology (area A), Affiliated Hospital of Inner Mongolia Medical University, Inner Mongolia, China. Electronic address:
Acta Biomater
March 2025
Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address:
Traditional methods of plasmid delivery, including viral vectors, lipofection, and electroporation, are widely used for gene editing but have limitations, such as cellular toxicity, limited transfection efficiency in primary cells, and nonspecific side effects. Here, we report the development of nucleus pulposus cell (NPC)-mimicking nanoparticles (HIF1A@NNP) with an NPC membrane as the shell and pcDNA3.1-rHIF1A encapsulated in the core via extrusion.
View Article and Find Full Text PDFCardiovasc Revasc Med
March 2025
Division of Cardiology, Department of Medicine, University of Washington, Seattle, WA, USA. Electronic address:
Background: The use of plaque modification techniques during percutaneous coronary interventions (PCI) has increased. However, these procedures are linked to higher contrast volume and hypotensive episodes, which are risk factors for acute kidney injury (AKI). This study examined the effects of various plaque modification techniques on AKI after PCI.
View Article and Find Full Text PDFCardiovasc Revasc Med
March 2025
FSCAI - Cleveland Clinic Main Campus, Cleveland, OH, United States of America.
Background: Chronic Limb Threat Ischemia (CLTI) is a severe form of peripheral arterial disease characterized by various symptoms including nonhealing wounds, ulcers and gangrene ultimately leading to a possible amputation. Therefore, revascularization either through endovascular intervention (EVI) or surgical bypass (SB) is an important step in management. Literature review of various studies including Randomized clinical trials (RCTs), Meta-analysis and observational studies show varied results with some studies suggesting better outcomes with EVI while majority of the others favors superiority of SB.
View Article and Find Full Text PDFUrol Oncol
March 2025
Department of Urology, Lausanne University Hospital, Lausanne, Switzerland. Electronic address:
Background And Objective: Our objective was to evaluate the agreement between micro-ultrasound, MRI and pathological tumor and prostate volume.
Methods: Retrospective analysis of consecutive prostate cancer patients with MRI and micro-ultrasound diagnostic assessment who subsequently underwent radical prostatectomy. Tumor and prostate volume on micro-ultrasound and MRI imaging calculated by a dedicated software were compared to those of the prostatectomy specimen.
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