Results of the patients treatment, in whom biliodigestive anastomosis was performed for hepatopancreatobiliary zone cancer, were adduced. Among early complications hepatorenal insufficiency, septic-purulent and thrombohemorrhagic complications, postoperative pancreatitis, an acute purulent cholangitis had prevailed. The late complications were mainly presented by the biliary ducts cicatricial stricture, the jaundice and cholangitis recurrency. To improve the results of treatment of early and late postoperative complications the complex of surgical and therapeutic prophylactic measures was proposed as well as the monitoring system, based on the active diagnostico-therapeutic tactics algorhythm elaborated, which was directed on revealing and removal of complications. The timely performance of relaparotomy and "second look" operation constitutes the principal surgical method used.

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