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Etiological features of status epilepticus of the in-patient cohort in Tibet: A retrospective comparative study.
Seizure
January 2025
Department of Neurology, West China Hospital of Sichuan University, Chengdu, Sichuan Province, PR China; Institute of Brain Science and Brain-Inspired Technology of West China Hospital, Sichuan University, Chengdu, Sichuan Province, PR China. Electronic address:
Background: The etiology of status epilepticus (SE) in Tibet has not yet been reported. We aimed to establish the etiological baseline of SE in the Tibet Autonomous Region in China and compare it with a SE cohort from a regional neuroscience centre in Sichuan, Southwestern China to reveal whether there was a unique etiology distribution in the Tibetan region.
Methods: We retrospectively captured clinical data of patients diagnosed with SE in the People's Hospital of Xizang Autonomous Region from January 2015 to December 2020.
Introduction: Epilepsy is one of the most common neurological conditions worldwide, with large variation in prevalence across Sub-Saharan Africa countries. Northern Uganda is one of the poorest areas of the country and has seen high density of pigs and prevalence of Taenia solium, a zoonotic tapeworm transmitted which cause neurocysticercosis in humans. The objective of this study was to estimate the population-level prevalence of active epilepsy in 25 sub-counties of northern Uganda.
View Article and Find Full Text PDFImmunologic Profiling of CSF in Subarachnoid Neurocysticercosis Reveals Specific Interleukin-10-Producing Cell Populations During Treatment.
Neurol Neuroimmunol Neuroinflamm
November 2024
From the Laboratory of Parasitic Diseases (N.L.T., P.G.-G., L.T., E.M., T.E.N., T.B.N., E.M.O.C.), Integrated Data Sciences Section (P.S., J.L.), National Institute of Allergy and Infectious Diseases; and Clinical Monitoring Research Program Directorate (L.T.), Frederick National Laboratory for Cancer Research.
Background And Objectives: Subarachnoid neurocysticercosis (SANCC) is the most severe form of CNS infection and accounts for the majority of neurocysticercosis-associated mortality. Inflammation is important in the treatment of SANCC because overactivity can lead to serious complications, but excessive suppression may be counterproductive toward parasite eradication. A relative abundance of CSF IL-10 to IL-12 has been associated with increased treatment duration for patients with SANCC, suggesting that IL-10 plays an important role in this disease process.
View Article and Find Full Text PDFMass chemotherapy with niclosamide for the control of : population-based safety profile and treatment effectiveness.
Lancet Reg Health Am
October 2024
Centro de Salud Global, Tumbes, Universidad Peruana Cayetano Heredia, Lima and Tumbes, Perú.
Background: Mass drug administration (MDA) with niclosamide (NSM) can be used to control taeniasis, the cause of neurocysticercosis. NSM is 84.3% effective against taeniasis and is considered safe as it is not absorbed from the intestinal tract.
View Article and Find Full Text PDFNeurocysticercosis and cognitive impairment among people with epilepsy in Taenia solium endemic regions of rural southern Tanzania: A hospital-based cross-sectional study in mental health clinics of selected sites in Tanzania.
Epilepsy Behav
October 2024
Department of Neurology, Technical University of Munich, Munich, Germany; Center for Global Health, Technical University of Munich, Munich, Germany; Department of Community Medicine and Global Health, Institute of Health and Society, University of Oslo, Oslo, Norway; Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA. Electronic address:
Background: Epilepsy poses a significant public health problem in many parts of the world. The majority of people with epilepsy (PWE) are from low-income and middle-income countries (LMICs). Taenia solium neurocysticercosis (NCC) is estimated to cause 30% of preventable epilepsy in PWE in areas of T.
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