[A new steroidal glycoside from fermented leaves of Agave americana].

Zhongguo Zhong Yao Za Zhi

State Key Laboratory of Phytochemistry and Western Plant Resources in China.

Published: June 2002

Objective: To investigate the constituents of fermented leaves of Agave americana, and discover new compounds.

Method: Compounds were purified with silica gel and C8 reverse--phase silica gel column chromatography. The structures were elucidated by chemical and spectroscopic evidence.

Result: Three steroidal compounds were obtained and their structures were identified as (25R)-5 alpha-spirostan-3 beta, 6 alpha, 23 alpha-triol 6-O-beta-D-glucopyranoside(1), (25R)-5 alpha-spirostan-3 beta, 6 alpha, 23 alpha-triol-3, 6-di-O-beta-D-glucopyranoside (cantalasaponin-1) (2) and (25R)-5 alpha-spirostan-3 beta, 6 alpha, 23 alpha-triol(hongguanggenin) (3).

Conclusion: Compound 1 is new compound, named agamenoside C.

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[A new steroidal glycoside from fermented leaves of Agave americana].

Zhongguo Zhong Yao Za Zhi

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State Key Laboratory of Phytochemistry and Western Plant Resources in China.

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Method: Compounds were purified with silica gel and C8 reverse--phase silica gel column chromatography. The structures were elucidated by chemical and spectroscopic evidence.

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