Purpose: To research the incidence of visual loss after laser in situ keratomileusis (LASIK).
Methods: We reviewed an extensive review of the literature published by The Ophthalmic Technology Assessment Committee of the American Academy of Ophthalmology regarding the safety and efficacy of LASIK. We also reviewed other recent literature.
Results: For low to moderate myopia and astigmatism, LASIK is efficient, safe, and predictable with few eyes losing two or more lines of best-corrected visual acuity (BCVA). For moderate to high myopia, the results are more variable and more eyes lost two or more lines BCVA. In both cases, this BCVA occurred in studies published on or before 1999.
Conclusion: Serious adverse complications leading to significant visual loss are probably rare. Continued development of microkeratomes and laser technology are continuing to reduce the rare complications that do occur and improve functional outcomes and patient satisfaction.
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http://dx.doi.org/10.1097/00140068-200301001-00036 | DOI Listing |
Se Pu
February 2025
CAS Key Laboratory of Separation Sciences for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
Chemical modifications are widely used in research fields such as quantitative proteomics and interaction analyses. Chemical-modification targets can be roughly divided into four categories, including those that integrate isotope labels for quantification purposes, probe the structures of proteins through covalent labeling or cross-linking, incorporate labels to improve the ionization or dissociation of characteristic peptides in complex mixtures, and affinity-enrich various poorly abundant protein translational modifications (PTMs). A chemical modification reaction needs to be simple and efficient for use in proteomics analysis, and should be performed without any complicated process for preparing the labeling reagent.
View Article and Find Full Text PDFEye Contact Lens
January 2025
Lewis Katz School of Medicine at Temple University (F.A.), Philadelphia, PA; and Wilmer Eye Institute (L.D.M., K.B., A.C.), Baltimore, MD.
Objective: To determine if scleral fittings that occur before corneal cross-linking (CXL) are still successful after the procedure.
Methods: This prospective study included seven patients with keratoconus or post-laser-assisted in situ keratomileusis (LASIK) corneal ectasia who were fitted with scleral lenses then underwent CXL. Four patients (six eyes) had keratoconus and three patients (five eyes) had post-LASIK ectasia.
Signal Transduct Target Ther
January 2025
Department of Ophthalmology, the Third Medical Center of Chinese PLA General Hospital, Beijing, China.
Dry eye disease (DED) is a prevalent inflammatory condition significantly impacting quality of life, yet lacks effective pharmacological therapies. Herein, we proposed a novel approach to modulate the inflammation through metabolic remodeling, thus promoting dry eye recovery. Our study demonstrated that co-treatment with mesenchymal stem cells (MSCs) and thymosin beta-4 (Tβ4) yielded the best therapeutic outcome against dry eye, surpassing monotherapy outcomes.
View Article and Find Full Text PDFProc Biol Sci
January 2025
Department of Anthropology, University College London, London, UK.
The distribution of self-awareness across species is important to understand, not only as a matter of scientific interest but also because of its implications for the ethical standing of non-human animals. The prevailing methodology for determining self-awareness is to test for visual self-recognition using mirror-image stimulation and a 'mark test'. However, most studies have involved very small sample sizes, omitted a control condition and been conducted on captive animals.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!