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Basic Science and Pathogenesis.
Alzheimers Dement
December 2024
College of Public Health, University of Kentucky, Lexington, KY, USA.
Background: Brain arteriolosclerosis (B-ASC) is a pathologic hallmark characterized by dysmorphic brain arteriolar wall thickening. B-ASC is a common finding at autopsy in aged persons - some degree of B-ASC is seen in >80% of brains beyond age 80 years - and is associated with cognitive impairment. Hypertension and diabetes are widely recognized as risk factors for B-ASC.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
Memory & Aging Center, Department of Neurology, University of California in San Francisco, San Francisco, CA, USA.
Background: Although frontotemporal dementia (FTD) with right anterior temporal lobe (RATL) predominance has been recognized as a separate FTD subtype, a uniform description of the syndrome is still missing. This multicenter study, led by an international working group (IWG), aims to establish a cohesive clinical phenotype and lay the groundwork for consensus on terminology and diagnostic standards.
Method: Retrospective clinical data were systematically collected across 18 dementia centers.
The Predictive Role of Maternal Serum Amyloid A in Preterm Birth: An Observational Study in Romania.
Cureus
December 2024
Department of Urology, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, ROU.
Background: Despite improvements in pregnancy care, preterm birth remains a major cause of neonatal morbidity and mortality worldwide, particularly in developing countries. Maternal inflammation has been recognized as a factor that may induce preterm birth, with various inflammatory markers associated with its pathogenesis. The aim of this study is to evaluate the value of maternal serum amyloid A(SAA) level as a predictive marker for preterm delivery in a Romanian cohort.
View Article and Find Full Text PDFA Giant Nevus Lipomatosus Cutaneous Superficialis Treated With Serial Surgical Excision: A Case Report.
Cureus
December 2024
Dermatology, Datta Meghe Medical College, Nagpur, IND.
Nevus lipomatosus cutaneous superficialis (NLCS) is a rare dermatological condition characterized by ectopic mature adipocytes in the dermis. The classic variety presents multiple clustered skin-colored nodules, while the solitary form is a single papule or nodule. We report the case of a 25-year-old female who presented with multiple cerebriform nodules coalescing into a large plaque over the left iliac region that developed over 17 months.
View Article and Find Full Text PDFAdvancing Innovation in Medical Presentations: A Guide for Medical Educators to Use Images Generated With Artificial Intelligence.
Cureus
December 2024
Department of Neurology, Gummersbach Teaching Hospital, University of Cologne, Gummersbach, DEU.
Multimedia learning theory suggests that the use of images in the classroom enhances both cognitive and constructive learning. Finding the appropriate images for medical presentations can be challenging due to copyright and privacy issues. Artificial intelligence (AI) image generation is a newly available technology that offers a great advantage to medical educators.
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