Objective: To describe clinical and pathological findings of a new case of juvenile gangrenous vasculitis of the scrotum, a peculiar and unusual (only 7 cases, approximately, have been previously reported) type of scrotal gangrene described by Piñol in 1973.
Methods: A 24 year-old male presented at the emergency room with a right scrotal necrotising cutaneous lesion and fever. Physical examination, complete blood count, biochemical test, roentgenographic abdominal and thoracic findings, microbiological test and biopsy were performed.
Results: Clinical aspects (symptoms and sings) and results of complete blood count (leukocytosis), normal ultrasound exploration and biochemical and roentgenographic abdominothoracic findings, microbiological test (negative) and biopsy (necrotising vasculitis) are compatible with juvenile gangrenous vasculitis of the scrotum.
Conclusions: Juvenile gangrenous vasculitis of the scrotum is a rare entity which should be diagnosed by strict clinicopathological diagnostic criteria because treatment and prognosis are distinct of other numerous ulcerative scrotal diseases.
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Ital J Dermatol Venerol
December 2024
Department of Dermatology, Istituto Dermopatico dell'Immacolata (IDI-IRCCS), Rome, Italy -
Mod Rheumatol Case Rep
December 2024
Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital Kajigaya, Kanagawa, Japan.
Polyarteritis nodosa (PAN) is a rare systemic necrotizing vasculitis that can lead to the formation of refractory lower limb ulcers requiring amputation. The standard treatment for severe PAN involves combination therapy with steroids and cyclophosphamide; however, some cases prove to be challenging. Recently, case reports have described the use of biological agents for PAN treatment.
View Article and Find Full Text PDFCase Rep Rheumatol
November 2024
Division of Rheumatology, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico, USA.
Tumor necrosis factor alpha inhibitors (TNFi) are biological drugs used worldwide to treat various autoimmune disorders. Paradoxically, TNF- antagonists can also induce autoimmune diseases being systemic vasculitis, systemic lupus erythematosus, and psoriasis, the most common. We present a 22-year-old woman with ulcerative colitis (UC) who was started on adalimumab 40 mg subcutaneously every 2 weeks.
View Article and Find Full Text PDFVasc Health Risk Manag
November 2024
Department of Physiology, Universitas Padjadjaran, Bandung, Indonesia.
Introduction: We present a case of late endograft infection that progressed to the left iliac and femoral arteries, leading to left lower extremity gangrene, and the patient's death.
Case: A 65-year-old male with a history of endovascular abdominal aortic aneurysm repair (EVAR) developed left acute limb ischemia (Rutherford category III) and abdominal pain. A CT scan showed significant gas formation around the endograft and complete occlusion of the left distal iliac artery to the femoral arteries.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
October 2024
Department of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi Guizhou, 563003, P. R. China.
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