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Condylar osseous changes following conservative therapies: A cone-beam computed tomography longitudinal study on adult patients with degenerative temporomandibular joint disease.
J Craniomaxillofac Surg
December 2024
State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China. Electronic address:
This retrospective study aimed to comprehensively investigate the impact of non-surgical treatments on condylar osseous changes in adult patients with degenerative joint disease (DJD). Radiographic and clinical data were collected for analysis. Cone-beam computed tomography (CBCT) was used to diagnose DJD, including flattening, erosion, osteophytes, sclerosis and cysts.
View Article and Find Full Text PDFEffect of Ultraviolet C light disinfection on the dimensional stability of dental impression materials: A scoping review of the literature.
J Clin Exp Dent
November 2024
DDS, PhD. Professor, Center for Dental Medicine, Clinic for Masticatory Disorders and Dental Biomaterials, University of Zurich, Zurich, Switzerland.
Background: Ultraviolet C (UVC) light is a physical method proposed for disinfecting dental impression materials and preventing cross-infections in clinical practice. The investigations have focused on the UVC disinfection potential, but little is known about the consequences on dental materials' properties. This scoping review's objective is to evaluate information about the effect of UVC light on the dimensional stability of dental impression materials.
View Article and Find Full Text PDFExploring the Inhibitory Potential of Compounds Against -Acetylglucosamine (Mur) Receptor: Insights Into Antibacterial Activity and Drug-Likeness.
ScientificWorldJournal
December 2024
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Bandung, Indonesia.
Oral diseases are often caused by bacterial infections, making the inhibition of receptors like -acetylglucosamine critical in preventing bacterial formation. The plant () is known for its diverse bioactivities and may serve as a promising source for developing new antibacterial agents. This study employs in silico methods to predict the inhibitory mechanisms, pharmacokinetics, and drug-likeness of compounds isolated from .
View Article and Find Full Text PDFNovel formulations ameliorate osteoarthritis in rats by inhibiting inflammation and oxidative stress.
Food Sci Nutr
October 2024
Department of Animal Nutrition, Faculty of Veterinary Medicine Firat University Elazig Turkey.
The study tested new oral plant-based formulations (F) on rats with monosodium iodoacetate (MIA)-induced osteoarthritis, measuring inflammation, antioxidant levels, paw size, stride, and analyzing knee joint images. Fifty-six female Sprague Dawley rats were allocated into 8 groups: (1) Control, (2) MIA (OA induced with MIA), (3) MIA + F1 [curcuminoids+gingerols+acetyl-11-keto-β boswellic acid (AKBA)], (4) MIA + F2 (curcuminoids+Withania glycosides+AKBA), (5) MIA + F3 (curcuminoids+total withanolides+AKBA), (6) MIA + F4 (curcuminoids, AKBA), (7) MIA + UCII (type II collagen), and (8) MIA + GCHON (Glucosamine Chondroitin). Treatments F1 to F4 reduced right joint diameter and improved stride length and paw area in OA rats.
View Article and Find Full Text PDFCarbapenem-Resistant Uses Mucus Metabolism to Facilitate Gastrointestinal Colonization.
bioRxiv
September 2024
Department of Microbiology, Genetics, & Immunology, Michigan State University, East Lansing, MI, 48824.
Article Synopsis
- Carbapenem-resistant species are a major public health concern, causing severe infections, particularly in vulnerable populations like newborns and immunocompromised individuals.
- The intestine may serve as a key reservoir for these bacteria, underscoring the need to understand how they colonize the gut to prevent infections.
- A new neonatal mouse model was created to study gut colonization, revealing important metabolic pathways and strategies used by these bacteria, which can inform future therapies for at-risk groups.
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