The acaricidal effects of tonka bean, Dipterix odorata, extracts were investigated on Dermatophagoides pteronyssinus, the European house dust mite, and compared with benzyl benzoate as a standard acaricidal compound. A cyclohexane extract was the most effective, with an EC(50) = 0.075 g/m(2) after a 24 h period, as compared with benzyl benzoate (0.025 g/m(2)). Bioassay-guided fractionation of this extract led to the isolation of coumarin (1). Pharmacomodulation of this compound led us to test 20 analogues (2-21), which were either synthesized or purchased.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/np020563j | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Maternal supplementation with Dipteryx alata Vog. modulates fecal microbiota diversity, accelerates reflex ontogeny, and improves non-associative and spatial memory in the offspring of rats.
Brain Res
December 2024
Program of Food Science and Technology, Federal University of Paraíba, João Pessoa, PB, Brazil; Laboratory of Experimental Nutrition, Department of Nutrition, Federal University of Campina Grande, Cuité, CG, Brazil.
Maternal diet plays a crucial role in offspring development, directly affecting neural development and gut microbiota composition. This study aimed to assess if baru almond and oil (Dipteryx alata Vog.) could modulate intestinal microbiota, brain fatty acid profile, and enhance memory in offspring of rats treated during early life stages.
View Article and Find Full Text PDFAnti-arthritic potential and antioxidant properties of infusion, fractions and flavonoid glycosides from Dipteryx alata (baru) leaves.
J Ethnopharmacol
February 2025
Federal University of Grande Dourados - UFGD, Faculty of Health Sciences, Postgraduate Program in Health Sciences, 79804-970, Dourados, Mato Grosso do Sul, Brazil. Electronic address:
Ethnopharmacological Relevance: Dipteryx alata Vogel., popularly known as "baru", is a native species of Brazilian cerrado used by "Ribeirinhos" in the North Araguaia microregion. In the traditional medicine, maceration of barks or leaves infusion are used to treat back and muscle pain, osteoporosis and rheumatism.
View Article and Find Full Text PDFUsing seasonal physiological and biochemical responses to select forest components adapted to soybean and corn intercropping.
Heliyon
August 2024
Instituto Federal de Educação, Ciência e Tecnologia Goiano, Rio Verde Campus, Rodovia Sul Goiana, Km 01, Zona Rural, Rio Verde, 75.901-970, GO, Brazil.
Given the increasing utilization of forest components in integration systems worldwide, coupled with the growing demand for food in regions facing water restrictions, this study aims to evaluate how physiological and biochemical parameters contribute to the diversification of adaptive mechanisms among native species and eucalyptus genotypes intercropped with soybean or corn. The native tree species and , and the eucalyptus genotypes Urograndis I-144 and Urocam VM01, were grown in soybean and corn intercropping areas and evaluated in fall, winter, spring, and summer. The study evaluated morning water potential, chloroplast pigment concentration, gas exchange, cell damage, and antioxidant enzyme activity.
View Article and Find Full Text PDFAdvances in the biosynthesis of tetraacetyl phytosphingosine, a key substrate of ceramides.
Synth Syst Biotechnol
July 2024
State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, No. 30 South Puzhu Road, Nanjing, 211816, People's Republic of China.
Article Synopsis
- Ceramides, crucial in skincare and pharmaceuticals, are derived from long-chain fatty acids and phytosphingosine, but sourcing phytosphingosine from plants is difficult due to low concentrations.
- The main method for producing phytosphingosine is through the deacetylation of tetraacetyl phytosphingosine (TAPS), which is primarily obtained from a specific yeast that can naturally secrete TAPS.
- Recent studies focus on enhancing TAPS production through methods like haploid breeding and metabolic engineering, and the review discusses advancements, challenges, and future research directions in this area.
Baru (Dipteryx alata): a comprehensive review of its nutritional value, functional foods, chemical composition, ethnopharmacology, pharmacological activities and benefits for human health.
Braz J Biol
August 2024
Universidade Federal da Grande Dourados - UFGD, Faculdade de Ciências da Saúde, Programa de Pós-graduação em Ciências da Saúde, Dourados, MS, Brasil.
Baru (Dipteryx alata Vogel) is recognized as a widespread Brazilian tree species, and its almonds and pulp have gained commercial prominence due to their nutritional value. All parts of the baru are important for the environment and are used by traditional communities to treat various diseases. This review provides a comprehensive and current overview of the nutritional composition, human food applications, ethnopharmacological uses, and chemical and biological properties of Dipteryx alata, "baru" (Fabaceae).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!