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Background: Drug usage in pregnant women is associated with a problem of possible negative influence on prenatal development. It is always necessary to judge the need for drug administration during pregnancy.
Objective: The aim of presented study was to analyse data about pregnant women hospitalized in the postpartum period.
Surgical treatment of neuronal-glial tumors of mesial-basal part of temporal lobe: Long term outcome and control of epilepsy in pediatric patients.
Neurol Neurochir Pol
May 2019
Department of Neurosurgery, The Children's Memorial Health Institute, Head: professor Marcin Roszkowski, Warsaw, Poland.
Background: Neuronal-glial tumors (ganglioglioma and dysembryoplastic neuroepithelial tumor) are a frequent cause of focal, drug-resistant and epilepsy in children and young adults, that is amenable for surgical treatment.
Aim Of Paper: Assessment of late outcome of surgical treatment and degree of seizure control, as well as prognostic significance of selected clinical factors.
Material And Method: 52 Pediatric patients presenting with epilepsy, lesion of mesio-basal temporal lobe and histologically verified neuronal-glial tumor treated at our facility since 2000-2011.
Adverse effects of statins - myths and reality.
Curr Pharm Des
September 2015
University of Zagreb, School of Medicine, University Hospital Center Zagreb, Department of Internal Medicine, Division of metabolic disease, Zagreb, Kispaticeva 12, Croatia.
Statins reduce cardiovascular mortality and morbidity as well as cardiovascular events in patients with a very high risk of cardiovascular disease (CVD) and also in subjects with high or moderate risk by reducing the levels of low-density lipoprotein cholesterol (LDL-C). Although they are considered to be drugs with a very good safety profile, because of their wide use there are many concerns that their adverse effects might compromise their proven beneficial effects. Therefore this article reviews all the data and provides an evidence- based insight what are the proven adverse effects of statins and what are the "myths" about them.
View Article and Find Full Text PDFPleiotropic effects of thiazolidinediones on traditional and non-traditional atherosclerotic risk factors.
Int J Clin Pract
June 2009
Department of Medicine, Rudolfstiftung Hospital, Vienna, Austria.
Background: The thiazolidinediones pioglitazone and rosiglitazone have established efficacy in improving insulin sensitivity, glycaemic control, dyslipidaemia, hypertension and microalbuminuria in patients with type 2 diabetes. As specific agonists of peroxisome proliferator-activated receptor-gamma, thiazolidinediones have also demonstrated protective effects on a variety of atherosclerosis biomarkers and surrogate measures of cardiovascular disease.
Aim: This paper reviews the evidence for pleiotropic effects on a variety of non-traditional atherosclerotic risk factors.
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