Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Cutaneous Rosai-Dorfman disease with MAP2K1 mutation, initially mimicking an infection with parasitized histiocytes.
J Cutan Pathol
December 2024
Department of Pathology, Virginia Commonwealth University Health System, Richmond, Virginia, USA.
Rarely, Rosai-Dorfman disease (RDD) manifests exclusively in the skin, typically as nodules on the trunk and extremities. Recognition of characteristic histopathologic features enables diagnosis of RDD. A 55-year-old female presented with a 7-year history of cutaneous nodules involving the trunk and extremities.
View Article and Find Full Text PDFBenign prostatic hyperplasia nodules in patients treated with celecoxib and/or finasteride have reduced levels of NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, a mitochondrial protein essential for efficient function of the electron transport chain.
Prostate
October 2024
Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Background: Benign prostatic hyperplasia (BPH) is a condition generally associated with advanced age in men that can be accompanied by bothersome lower urinary tract symptoms (LUTS) including intermittency, weak stream, straining, urgency, frequency, and incomplete bladder voiding. Pharmacotherapies for LUTS/BPH include alpha-blockers, which relax prostatic and urethral smooth muscle and 5ɑ-reductase inhibitors such as finasteride, which can block conversion of testosterone to dihydrotestosterone thereby reducing prostate volume. Celecoxib is a cyclooxygenase-2 inhibitor that reduces inflammation and has shown some promise in reducing prostatic inflammation and alleviating LUTS for some men with histological BPH.
View Article and Find Full Text PDFDifferences in hidradenitis suppurativa patterns of cutaneous involvement between sexes: Insights from a cross-sectional study.
Hum Immunol
March 2024
Department of Anatomy, Faculty of Medicine and Surgery, University of Malta, Msida, Malta; Centre for Molecular Medicine and Biobanking, University of Malta, Msida, Malta.
Hidradenitis suppurativa is a chronic, inflammatory condition of the pilosebaceous unit in which patients manifest multiple, painful cutaneous nodules, abscesses and tunnels. These lesions are described to affect the intertriginous zones, however, the condition exhibits significant phenotypic variability. Such variability is influenced by the patients lifestyle, genetic predisposition and sex.
View Article and Find Full Text PDFAn overview of myofascial pain syndrome with a focus on trigger point injection.
Nurse Pract
November 2023
Nicole Bodine is a family NP with the Defense Health Agency, currently serving as a provider in the Pain Clinic at Evans Army Community Hospital in Colorado Springs, Colo.
Myofascial pain syndrome (MPS) is a very common condition, with an estimated lifetime prevalence of 85% in the general population. MPS is commonly underdiagnosed or misdiagnosed due to the lack of standardized diagnostic criteria and the symptoms' overlap with those of other musculoskeletal pain conditions. The most notable and bothersome feature of MPS is the presence of myofascial trigger points (MTrPs), hypersensitive areas of muscle commonly characterized as knots, nodules, or bumps that cause strain and pain with and oftentimes without stimulation.
View Article and Find Full Text PDFPerspectives of adolescents with neurofibromatosis 1 and cutaneous neurofibromas: Implications for clinical trials.
Clin Trials
February 2024
Department of Neurology and Cancer Center, Massachusetts General Hospital, Boston, MA, USA.
Article Synopsis
- This study examines the perspectives of adolescents with neurofibromatosis 1 (NF1) and their caregivers regarding cutaneous neurofibromas, which are benign tumors that commonly develop on the skin.
- The research involved an online survey of 28 adolescents and 32 caregivers, collecting data on the emotional and social impacts of these tumors, as well as their views on treatment options and associated risks.
- Results indicated that many adolescents felt concerned about their neurofibromas, especially regarding their appearance and potential progression, with a significant majority favoring topical and oral medications as treatment options.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!