Objective: To understand the clinical presentation, management, and natural history of paranasal rhabdomyosarcoma.
Design: Retrospective case series review.
Methods: Retrospective medical record review of patients less than 20 years of age who presented to our facility with rhabdomyosarcoma of the nasal cavity or paranasal sinuses.
Results: Medical records of all pediatric patients seen in our pediatric otolaryngology clinic were reviewed from January 1, 1995, through December 31, 2000. Three patients were identified with sinonasal rhabdomyosarcoma. Their presentation, evaluation, and treatment were evaluated. Relevant literature 1966 to the present was reviewed with the assistance of Medline.
Conclusions: Rhabdomyosarcoma is an aggressive pediatric malignancy, requiring a high index of suspicion to detect it in its earliest stages. Patients with suggestive symptoms should undergo a full evaluation including nasal endoscopy and imaging. Because the current chemotherapy protocols are more effective on localized disease, early diagnosis is crucial to patient survival.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0196-0709(03)00025-5 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Sinonasal Specific Bone Lesions, Including Fibro-Osseous and Select Odontogenic Lesions.
Surg Pathol Clin
December 2024
Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA; Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA. Electronic address:
Sinonasal bone lesions encompass a diverse spectrum, ranging from nonneoplastic and benign conditions to aggressive, malignant neoplasms. These lesions can affect individuals across various age groups, from pediatric to adult patients. Recognizing these entities is crucial, given the variability in treatment approaches, recurrence rates, and prognoses.
View Article and Find Full Text PDFPropofol-induced transient arginine vasopressin deficiency.
Endocrinol Diabetes Metab Case Rep
October 2024
Southern Adelaide Diabetes and Endocrine Service, Flinders Medical Centre, Bedford Park, South Australia, Australia.
Summary: We describe and characterise the case of a 26-year-old female undergoing surgery for a right-sided sinonasal alveolar rhabdomyosarcoma who developed profound, transient arginine vasopressin deficiency (AVP-D, formerly central diabetes insipidus (DI)) associated with anaesthesia. In this case report, we characterise the development of AVP-D with serial copeptin and paired urine and serum osmolality measurements. Based on the anaesthetic agent's profile and the literature, we attribute this presentation to propofol exposure.
View Article and Find Full Text PDFPrimary Mast Cell Sarcoma of the Maxillary Sinus and Gingiva Mimicking Malignant Neuroendocrine Tumor: A Case Report.
Head Neck Pathol
October 2024
Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Rd, Taipei City, 112201, Taiwan.
Mast cell sarcoma (MCS) is an extremely rare and aggressive malignancy primarily affecting bones, with limited literature associating it with neuroendocrine marker expression. This report presents a rare case of MCS arising in the maxillary sinus and gingiva. A 74-year-old man presented with a progressively enlarging ulcer on the right-sided upper gingiva.
View Article and Find Full Text PDFRadiologic overview of sinonasal lesions.
Front Radiol
August 2024
Department of Imaging Sciences, University of Rochester Medical Center, Rochester, NY, United States.
Article Synopsis
- - Sinonasal tumors, which make up about 3% of head and neck cancers, often develop in the nasal cavity, ethmoid, and maxillary sinuses, with symptoms like headaches, nosebleeds, and vision changes.
- - Diagnostic imaging techniques like CT and MRI are crucial for locating tumors, assessing their invasion into surrounding tissues, and planning treatment.
- - The study will highlight various sinonasal tumors, including rare cases, focusing on their imaging features and the impact of tumor invasion on nearby structures, leading to neurological symptoms.
Sinonasal alveolar rhabdomyosarcoma with fusion expressing SOX10 and with nodal metastases: a double diagnostic pitfall.
J Clin Pathol
August 2024
School of Medicine and Population Health, The University of Sheffield, Sheffield, UK
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!