The stability of cefepime during simulated continuous infusion was determined with a motorized portable infusion pump worn over a period of 24 to 36 h. Susceptibility testing on cefepime solutions over time indicates that the degradation products do not exhibit antibacterial activity. Cefepime stability at 24 h following continuous infusion was 94.3% +/- 1.0%, which supports the use of continuous infusion.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC155835PMC
http://dx.doi.org/10.1128/AAC.47.6.1991-1994.2003DOI Listing

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