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Exploration of the metabolomic mechanisms of postmenopausal hypertension induced by low estrogen state.
Elife
January 2025
Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Estrogen significantly impacts women's health, and postmenopausal hypertension is a common issue characterized by blood pressure fluctuations. Current control strategies for this condition are limited in efficacy, necessitating further research into the underlying mechanisms. Although metabolomics has been applied to study various diseases, its use in understanding postmenopausal hypertension is scarce.
View Article and Find Full Text PDFKisspeptin and Neurokinin B: roles in reproductive health.
Physiol Rev
January 2025
Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.
Kisspeptin and neurokinin B (NKB) play a key role in several physiological processes including in puberty, adult reproductive function including the menstrual cycle, as well as mediating the symptoms of menopause. Infundibular kisspeptin neurons, which co-express NKB, regulate the activity of gonadotropin releasing hormone (GnRH) neurons, and thus the physiological pulsatile secretion of GnRH from the hypothalamus. Outside of their hypothalamic reproductive roles, these peptides are implicated in several physiological functions including sexual behavior and attraction, placental function, and bone health.
View Article and Find Full Text PDFThe relationship between sexual health literacy and sexual function of women with diabetes mellitus: a cross-sectional study.
J Sex Med
January 2025
Department of Gynecology and Obstetrics, Health Sciences University Ankara Training and Research Hospital, Ankara Altındağ 06230, Türkiye.
Background: Sexual dysfunction (SD) is a complication of poorly managed diabetes mellitus (DM). To prevent SD, patients should develop sexual health literacy (SHL).
Objective: This study investigated the relationship between SHL and SD in women with DM.
Assessing the influence of recurrent urinary tract infections on sexual function: a case-control study.
J Sex Med
January 2025
Department of Urology, Hospital Universitario 12 de Octubre-imas12, Madrid, 28040, Spain.
Background: Urinary tract infections (UTIs) significantly impact quality of life and can also lead to changes in sexual function.
Aim: This study aims to assess the symptoms associated with recurrent urinary tract infections (rUTIs) and their influence on both quality of life and sexual activity.
Methods: A case-control study was conducted, involving 383 patients with rUTIs and 161 healthy controls.
A bio-psycho-social investigation of menopause transition and job satisfaction.
Maturitas
December 2024
Department of Management, Birmingham Business School, University House, Birmingham B15 2TT, UK. Electronic address:
Objectives: To examine the implications of menopause transition for job satisfaction within a framework that integrates bio-psycho-social factors and effects.
Study Design: The study analyses quantitative and qualitative data from a survey of 1684 women in three UK police forces, where growing numbers work during menopause transition within what has been termed a hyper-masculine culture.
Results: We evidence that job satisfaction is negatively impacted by experience of menopause symptoms.
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