Rheology of concentrated suspensions of deformable elastic particles such as human erythrocytes.

J Biomech

Department of Chemical Engineering, University of Waterloo, 200 University Avenue West, Waterloo, Ont., Canada N2L 3G1.

Published: July 2003

AI Article Synopsis

  • New models using the differential effective medium approach (DEMA) have been created to understand the viscosity of concentrated suspensions of elastic particles, particularly human red blood cells (RBCs).
  • These models predict shear-thinning behavior as the shear rate increases, showing a decrease in relative viscosity similar to observations in actual RBC suspensions.
  • Findings suggest that lower particle rigidity or higher viscosity of the continuous medium enhances shear-thinning, aligning with experimental data from normal and hardened RBCs in saline.

Article Abstract

New models for the viscosity of concentrated suspensions of deformable elastic particles are developed using the differential effective medium approach (DEMA). The models are capable of describing the rheological behavior of un-aggregated suspensions of human red blood cells (RBCs). With the increase in shear rate, a shear-thinning behavior is predicted similar to that observed in the case of un-aggregated suspensions of RBCs. A decrease in relative viscosity and an enhancement of shear-thinning behavior is predicted when either the particle rigidity (elastic modulus) is decreased or the continuous medium viscosity is increased. These predictions are similar to those observed in suspensions of human RBCs. The proposed models are evaluated using experimental data on normal and hardened human RBC suspensions in protein-free saline.

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0021-9290(03)00067-8DOI Listing

Publication Analysis

Top Keywords

concentrated suspensions
8
suspensions deformable
8
deformable elastic
8
elastic particles
8
un-aggregated suspensions
8
suspensions human
8
shear-thinning behavior
8
behavior predicted
8
suspensions
6
rheology concentrated
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!