Objective: To study in vivo calcification and biomechanics of the ultra-microporous expanded polytetrafluo- roethylene (UePTFE) in rabbits in comparison with glutaral-treated bovine pericardium (BP), so as to assess the potential of UePTFE as a material for cardiac valve prosthesis.
Methods: Factorial analysis was adopted in the experiment. UePTFE and glutaral-treated BP of appropriate sizes were embedded beneath skin of young New Zealand rabbits, and at 0, 1, 3 and 6 months following the implantation, the materials were measured for the content of calcium and biomechanics properties.
Results: Lower level of calcification of the UePTFE occurred after the implantation, as compared with BP, and the biomechanics indices of the former UePTFE were obviously suprior to those of the latter.
Conclusion: UePTFE is a better material than BP for cardiac valve prosthesis.
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[Calcification and biomechanics in vivo of ultra-microporous expanded polytetrafluoroethylene in rabbits].
Di Yi Jun Yi Da Xue Xue Bao
May 2003
Department of Cardiothoracic Surgery, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.
Objective: To study in vivo calcification and biomechanics of the ultra-microporous expanded polytetrafluo- roethylene (UePTFE) in rabbits in comparison with glutaral-treated bovine pericardium (BP), so as to assess the potential of UePTFE as a material for cardiac valve prosthesis.
Methods: Factorial analysis was adopted in the experiment. UePTFE and glutaral-treated BP of appropriate sizes were embedded beneath skin of young New Zealand rabbits, and at 0, 1, 3 and 6 months following the implantation, the materials were measured for the content of calcium and biomechanics properties.
Hydrodyamical assessment of valve prosthesis made of expanded ultra-microporous Teflon in vitro.
Di Yi Jun Yi Da Xue Xue Bao
October 2002
Department of Cardiothoracic Surgery, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.
Objective: To assess the hydrodynamical performance of the valve prosthesis made of expanded ultra-microporous Teflon in vitro.
Method: Sheets of the expanded ultra-microporous Teflon were sewn onto flexible bracket to prepare artificial valve prosthesis. The leakage and steady flow of the valve prosthesis was tested in vitro with Baxter valve prosthesis as control.
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