This review article highlights the most important contributions presented at the 5th Copenhagen Workshop on Carcinoma in situ and Cancer of the Testis, which was held in Denmark, August 29-31, 2002. The major themes that emerged at the meeting are critically discussed and perspectives for future research in this field are presented.
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http://dx.doi.org/10.1034/j.1600-0463.2003.1110131.x | DOI Listing |
Methods Mol Biol
January 2025
Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK.
Metabolic profiling continues to develop, and research is now conducted on this topic globally in hundreds of laboratories, from small groups up to national centers and core facilities. Here we briefly provide a perspective on the current status and challenges facing metabolic phenotyping (metabonomics/metabolomics) and consider future directions for this important area of biomarker and systems biology research.
View Article and Find Full Text PDFAnn Nucl Med
January 2025
Department of Biomedical Sciences, Humanitas University, Milan, Italy.
The purpose of this systematic review was to evaluate the role of PSMA PET/CT in intermediate-risk prostate cancer (PCa) patients, to determine whether it could help improve treatment strategy and prognostic stratification. A systematic literature search up to May 2024 was conducted in the PubMed, Embase and Scopus databases. Articles with mixed risk patient populations, review articles, editorials, letters, comments, or case reports were excluded.
View Article and Find Full Text PDFEnviron Monit Assess
January 2025
Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing, 100101, China.
The study of land cover dynamics and the valuation of ecosystem services in coastal cities is pivotal for guiding sustainable urban development and conserving natural resources amidst the unique challenges posed by their geographical and ecological contexts. This study utilizes a 30 m × 30 m land use/cover change (LUCC) dataset to elucidate the spatiotemporal evolution of LUCC and ecosystem service value (ESV) and the trade-offs and synergistic relationships among ecosystem services in the coastal city of Qingdao under three different scenarios over the past 35 years and in the future based on the dual perspective of the past-future by using the equivalent factor approach (EFA), the PLUS model, and Spearman's rank correlation coefficient. The findings reveal a pronounced expansion in built-up areas in Qingdao from 1985 to 2020, with a concomitant significant reduction in cropland, leading to a fluctuation in the total ESV, which initially increased and then declined.
View Article and Find Full Text PDFACS Nano
January 2025
Department of Chemistry, Seoul National University, Gwanak-ro 1, Gwanak-gu, Seoul 08826, South Korea.
Surface-enhanced Raman scattering has been widely used for molecular/material characterization and chemical and biological sensing and imaging applications. In particular, plasmonic nanogap-enhanced Raman scattering (NERS) is based on the highly localized electric field formed within the nanogap between closely spaced metallic surfaces to more strongly amplify Raman signals than the cases with molecules on metal surfaces. Nanoparticle-based NERS offers extraordinarily strong Raman signals and a plethora of opportunities in sensing, imaging and many different types of biomedical applications.
View Article and Find Full Text PDFACS Nano
January 2025
Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea.
Optical metasurfaces, components composed of artificial nanostructures, are recognized for pushing boundaries of wavefront manipulation while maintaining a lightweight, compact design that surpasses conventional optics. Such advantages align with the current trends in optical systems, which demand compact communication devices and immersive holographic projectors, driving significant investment from the industry. Although interest in commercialization of optical metasurfaces has steadily grown since the initial breakthrough with diffraction-limited focusing, their practical applications have remained limited by challenges such as, massive-production yield, absence of standardized evaluation methods, and constrained design methodology.
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