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Debridement Technique for Single-Stage Revision Shoulder Arthroplasty.
JBJS Essent Surg Tech
January 2025
Shoulder and Elbow Service, Florida Orthopaedic Institute, Tampa, Florida.
Background: The incidence of revision shoulder arthroplasty continues to rise, and infection is a common indication for revision surgery. Treatment of periprosthetic joint infection (PJI) in the shoulder remains a controversial topic, with the literature reporting varying methodologies, including the use of debridement and implant retention, single-stage and 2-stage surgeries, antibiotic spacers, and resection arthroplasty. Single-stage revision has been shown to have a low rate of recurrent infection, making it more favorable because it precludes the morbidity of a 2-stage operation.
View Article and Find Full Text PDFBranched Linkers for Homogeneous Antibody-Drug Conjugates: How Long Is Long Enough?
Int J Mol Sci
December 2024
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, 117997 Moscow, Russia.
Homogeneous antibody-drug conjugates (ADCs) exhibit significantly improved pharmacological properties compared to their heterogeneous counterparts. Site-specific conjugation of the payload to the IgG required for homogeneity can be achieved using enzymes. One example is microbial transglutaminase (MTGase), which can selectively perform transamidation on the Q295 residue of human Fc when N297 glycans are removed.
View Article and Find Full Text PDFEvaluation of Pedicle Screw Position on Computerized Tomography Using Three-Dimensional Reconstruction Software.
Medicina (Kaunas)
December 2024
Spine Center and Department of Orthopedic Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Republic of Korea.
: Recent advances in intraoperative navigation systems have improved the accuracy of pedicle screw placement in spine surgery. However, many hospitals have limited access to these advanced technologies due to resource constraints. In such settings, postoperative computed tomography (CT) evaluation remains crucial for assessing screw placement and related potential complications.
View Article and Find Full Text PDFAn innovative complex-valued encoding black-winged kite algorithm for global optimization.
Sci Rep
January 2025
School of Electrical and Photoelectronic Engineering, West Anhui University, Lu'an, 237012, China.
The black-winged kite algorithm (BKA) constructed on the black-winged kites' migratory and predatory instincts is a revolutionary swarm intelligence method that integrates the Leader tactic with the Cauchy variation procedure to retrieve the expansive appropriate convergence solution. The essential BKA exhibits marginalized resolution efficiency, inferior assessment precision, and stagnant sensitive anticipation. To foster aggregate discovery intensity and advance widespread computational efficacy, an innovative complex-valued encoding BKA (CBKA) is presented to resolve the global optimization.
View Article and Find Full Text PDF"Central retinal artery occlusion following scleral buckling surgery with gas insertion in a patient with sickle cell disease".
Retin Cases Brief Rep
January 2025
Manchester Manchester Royal Eye Hospital, Manchester University Hospitals NHS Foundation Trust, Manchester, UK.
Purpose: To describe a case of central retinal artery occlusion following scleral buckling procedure combined with pneumoretinopexy in a patient with sickle cell (HbSC) retinopathy (SCR).
Methods: Scleral buckling procedure, combined with injection of 0.3 ml of 100% perfluoropropane (C3F8) gas in the vitreous, was performed without intra-operative complications under general anaesthesia as treatment of two separate macula-sparing rhegmatogenous retinal detachments secondary to round holes, involving superior and inferior retina respectively, in the right eye of a 26-year-old Afro-Caribbean female with sickle cell disease.
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