An association between HLA-DR13 and patients with complex regional pain syndrome (CRPS) who progressed towards multifocal or generalized tonic dystonia was recently reported. We now report on a new locus, centromeric in HLA-class I, which was significantly associated with a spontaneous development of CRPS, suggesting an interaction between trauma severity and genetic factors conferring CRPS susceptibility. Additionally, an association with the D6S1014 locus was found, supporting the previous finding of an association with HLA-DR13.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0304-3959(02)00444-x | DOI Listing |
Publication Analysis
Top Keywords
complex regional
8
regional pain
8
pain syndrome
8
association hla-dr13
8
susceptibility loci
4
loci complex
4
syndrome association
4
hla-dr13 patients
4
patients complex
4
syndrome crps
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!