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Dynamics of affect modulation in neurodevelopmental disorders (DynAMoND) - study design of a prospective cohort study.
Int J Bipolar Disord
December 2024
Department for Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt-Goethe University, Frankfurt am Main, Germany.
Background: Attention-deficit/hyperactivity disorder (ADHD) is a common neuro-developmental disorder that often persists into adulthood. Moreover, it is frequently accompanied by bipolar disorder (BD) as well as borderline personality disorder (BPD). It is unclear whether these disorders share underlying pathomechanisms, given that all three are characterized by alterations in affective states, either long or short-term.
View Article and Find Full Text PDFGold nanoclusters/manganese dioxide nanosheets hybrid nanozyme with fluorescence and oxidase-like activity for dual-mode detection of acetylcholinesterase and inhibitors screening.
Anal Bioanal Chem
December 2024
College of Pharmacy, Key Laboratory of Innovative Drug Development and Evaluation, Hebei Medical University, Shijiazhuang, 050017, China.
The abnormal expression of acetylcholinesterase (AChE) is linked to the development of various diseases. Accurate determination of AChE activity as well as screening AChE inhibitors (AChEIs) holds paramount importance for early diagnosis and treatment of AChE-related diseases. Herein, a fluorescent and colorimetric dual-channel probe based on gold nanoclusters (AuNCs) and manganese dioxide nanosheets (MnO NSs) was developed.
View Article and Find Full Text PDFMulti-sensor fusion and segmentation for autonomous vehicle multi-object tracking using deep Q networks.
Sci Rep
December 2024
School of Electronics Engineering, Vellore Institute of Technology, Vellore, India.
Autonomous vehicles, often known as self-driving cars, have emerged as a disruptive technology with the promise of safer, more efficient, and convenient transportation. The existing works provide achievable results but lack effective solutions, as accumulation on roads can obscure lane markings and traffic signs, making it difficult for the self-driving car to navigate safely. Heavy rain, snow, fog, or dust storms can severely limit the car's sensors' ability to detect obstacles, pedestrians, and other vehicles, which pose potential safety risks.
View Article and Find Full Text PDFA cross-sectional study assessing customers' perception, satisfaction, and attitude toward e-pharmacy services in Saudi Arabia.
BMC Health Serv Res
December 2024
Clinical Pharmacy Department, College of Pharmacy, King Khalid University, Abha, Saudi Arabia.
Background: Electronic pharmacy (e-pharmacy) services are growing rapidly, offering increased accessibility, privacy, and value. Understanding e-pharmacy customer satisfaction, attitudes, and perceptions in Saudi Arabia is crucial for improving the services and enhancing health outcomes. This study aims to examine customers' perceptions, preferences, satisfaction, and experiences with electronic pharmacy services, including community pharmacy e-commerce.
View Article and Find Full Text PDFPrevalence and factors associated with teenage pregnancy in refugee settlements of northern Uganda post-COVID-19 (2020-2023): a cross-sectional study.
BMJ Open
December 2024
Reproductive Health, Gulu University, Gulu, Uganda.
Background: Following the COVID-19 pandemic, there was an increase in teenage pregnancies nationally, however, limited data exists regarding the same among girls living in refugee settlements.
Objectives: We evaluated the prevalence of teenage pregnancy and associated factors in Palorinya and Bidi Bidi refugee settlements in Obongi and Yumbe districts of northern Uganda, in the post-COVID-19 era.
Design: We conducted a cross-sectional study.
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