The collagen fibers and proteoglycans in the disc of temporomandibular joint provide resistance to various loadings. Thus far, however, the role of the proteoglycans in determining the viscoelastic properties of the disc has not been investigated. In the present study the hypothesis was tested that the viscoelastic behavior of the disc decreases by the removal of proteoglycans. In 32 bovine discs, dynamic tensile tests with a wide range of frequencies were performed. Before testing, specimens were treated with different concentrations of alpha-amylase to remove proteoglycans. As the frequency increased from 0.1 to 100 Hz, the disc became more viscoelastic. Increasing the concentration of alpha-amylase significantly decreased its viscoelasticity. It was concluded that proteoglycans play an important role in determining the viscoelastic properties of the disc and, therefore, give the disc a greater capacity for distributing and reducing stresses.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/jbm.a.10496 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
formation of ultrahigh molecular weight polymers in highly concentrated electrolytes and their physicochemical properties.
Soft Matter
January 2025
Research Center for Macromolecules & Biomaterials, National Institute for Materials Science, 1-2-1 Sengen, Tsukuba 305-0047, Japan.
We developed a facile one-pot method for fabricating physical gels consisting of ultrahigh molecular weight (UHMW) polymers and highly concentrated lithium salt electrolytes. We previously reported physical gels formed from the entanglement of UHMW polymers by radical polymerisation in aprotic ionic liquids. In this study, we found that the molecular weight of methacrylate polymers formed by radical polymerisation increased with the concentration of lithium salts in the organic solvents.
View Article and Find Full Text PDFStereomicrostructure-regulated biodegradable adhesives.
Science
January 2025
Department of Chemistry, Colorado State University, Fort Collins, CO, USA.
Commercial adhesives are petroleum-based thermoset networks or nonbiodegradable thermoplastic hot melts, making them ideal targets for replacement by biodegradable alternatives. Poly(3-hydroxybutyrate) (P3HB) is a biorenewable and biodegradable alternative to conventional plastics, but microbial P3HB, which has a stereoperfect stereomicrostructure, exhibits no adhesion. In this study, by elucidating the fundamental relationship between chemocatalytically engineered P3HB stereomicrostructures and adhesion properties, we found that biodegradable syndio-rich P3HB exhibits high adhesion strength and outperforms common commercial adhesives, whereas syndiotactic, isotactic, or iso-rich P3HB shows no measurable adhesion.
View Article and Find Full Text PDFResonance-Induced Therapeutic Technique for Skin Cancer Cells.
Ultrasound Med Biol
January 2025
Institute of Biomedical Technologies, Auckland University of Technology, Auckland City, 1010, Auckland, New Zealand. Electronic address:
Objective: This study aims to evaluate the viability of a hypothesis for selective targeting of skin cancer cells by exploiting the spectral gap with healthy cells using analytical and numerical simulation.
Methods: The spectral gap was first identified using a viscoelastic dynamic model, with the physical and mechanical properties of healthy and cancerous skin cells deduced from previous experimental studies conducted on cell lines. The outcome of the analytical simulation was verified numerically using modal and harmonic analysis.
The human patellar tendon is mechanically homogenous at its mid-substance.
J Mech Behav Biomed Mater
December 2024
Department of Technical Physics, University of Eastern Finland, Kuopio, Finland.
The human patellar tendon contains distinct fascicle bundles across its mediolateral and anteroposterior regions. Studies have suggested region-specific behaviour during in vivo actions, but it is unclear whether such regional differences result from localized variation in composition and mechanical properties within the tendon itself. Furthermore, the viscoelastic properties of any region of the human patellar tendon have not been well described previously.
View Article and Find Full Text PDFA Combined Approach to Extract Rotational Dynamics of Globular Proteins Undergoing Liquid-Liquid Phase Separation.
J Phys Chem B
January 2025
Department of Physical Chemistry, Sciences II, University of Geneva, 30 Quai Ernest Ansermet, Geneva 1211, Switzerland.
The formation of protein condensates (droplets) via liquid-liquid phase separation (LLPS) is a commonly observed phenomenon in vitro. Changing the environmental properties with cosolutes, molecular crowders, protein partners, temperature, pressure, etc. has been shown to favor or disfavor the formation of protein droplets by fine-tuning the water-water, water-protein, and protein-protein interactions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!