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Multiple Epstein-Barr virus infections in healthy individuals. | LitMetric

AI Article Synopsis

  • * In our study, we found that two out of nine individuals were infected with as many as five different EBV genotypes.
  • * These findings suggest that multiple EBV infections in healthy individuals are more common than previously thought, which raises important considerations for developing an EBV vaccine.

Article Abstract

We employed a newly developed genotyping technique with direct representational detection of LMP-1 gene sequences to study the molecular epidemiology of Epstein-Barr virus (EBV) infection in healthy individuals. Infections with up to five different EBV genotypes were found in two of nine individuals studied. These results support the hypothesis that multiple EBV infections of healthy individuals are common. The implications for the development of an EBV vaccine are discussed.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC155020PMC
http://dx.doi.org/10.1128/jvi.77.11.6546-6550.2003DOI Listing

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