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Clinical Manifestations.
Alzheimers Dement
December 2024
Neuropsychology and Clinical Neuroscience Laboratory (LANNEC), Physiopathology Department - ICBM, Neuroscience and East Neuroscience Departments, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Background: The most common and prevalent dementia worldwide is Alzheimer's disease (AD). AD is a continuum composed of Subjective Cognitive Impairment (SCD), Mild Cognitive Impairment (MCI), and Alzheimer's Disease dementia (ADD) stage. One of the main clinical variables in patients with dementia is performance in functional capacity since its alterations are associated with poor prognosis and disease progression.
View Article and Find Full Text PDFLife course socioeconomic position and care dependency in later life: a longitudinal multicohort study from 17 countries.
EClinicalMedicine
January 2025
Center for Smart and Healthy Buildings, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
Background: Care dependency, inability to perform basic daily tasks without assistance due to functional impairment, increases substantially with accelerated population ageing and becomes a pressing public health concern worldwide. Socioeconomic disadvantage has been shown to be associated with elevated risks of care dependency, but how risks are modified by changes in socioeconomic position remains unclear. From a life course perspective, we investigated the association between socioeconomic mobility across the lifespan and care dependency in later life.
View Article and Find Full Text PDFChanges in daily stress reactivity and changes in physical health across 18 years of adulthood.
Ann Behav Med
December 2024
Department of Human Development and Family Studies, Pennsylvania State University, University Park, PA, 16803, United States.
Background: Stress plays a pivotal role in physical health. Although many studies have linked stress reactivity (daily within-person associations between stress exposure and negative affect) to physical health outcomes, we know surprisingly little about how changes in stress reactivity are related to changes in physical health.
Purpose: The current study examines how change in stress reactivity over 18 years is related to changes in functional health and chronic health conditions.
Intrinsic Capacity and Life Quality Among Taiwanese Older People: A Cross-Sectional Study.
OTJR (Thorofare N J)
December 2024
International Gaming Research Unit, Psychology Department, Nottingham Trent University, Nottingham, UK.
Intrinsic capacity (IC), an internal composite ability proposed by the World Health Organization, is fundamental to older people's health. The present study examined potential models explaining the association between IC and quality of life (QoL) among older people in Taiwan. Frailty, basic activities of daily living (BADL), and instrumental activities of daily living (IADL) were hypothesized to be mediators in the association between IC and QoL.
View Article and Find Full Text PDFFunctional dependency and cardiometabolic multimorbidity in older people: pooled analysis of individual-level data from 20 countries.
Age Ageing
November 2024
Heidelberg Institute of Global Health, Universitätsklinikum Heidelberg, Heidelberg, Baden-Württemberg, Germany.
Background: The impact of cardiometabolic multimorbidity (CMM) on functional dependency (FD) is well established, but the temporal effect of FD on CMM and its mechanisms remain underexplored.
Design: A multicohort study pooled data from three international cohorts.
Setting: Data were sourced from the Health and Retirement Study (USA), the China Health and Retirement Longitudinal Study (China) and the Survey of Health, Ageing and Retirement in 18 European countries.
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