Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Effect of Metformin on Meibomian Gland Epithelial Cells: Implications in Aging and Diabetic Dry Eye Disease.
Life (Basel)
December 2024
Institute of Functional and Clinical Anatomy, Friedrich-Alexander University Erlangen-Nürnberg, 91054 Erlangen, Germany.
Background: Metformin, a commonly prescribed medication for managing diabetes, has garnered increasing interest as a potential therapeutic option for combating cancer and aging.
Methods: The current study investigated the effects of metformin treatment on human meibomian gland epithelial cells (hMGECs) at morphological, molecular, and electron microscopy levels. HMGECs were stimulated in vitro with 1 mM, 5 mM, and 10 mM metformin for 24, 48, and 72 h.
Morphology of the Human Pineal Gland Studied by Freeze-Fracturing in Scanning Electron Microscopy.
Life (Basel)
December 2024
Institute of Histology and Embryology, Faculty of Medicine, Comenius University in Bratislava, Špitálska Street 24, 813 72 Bratislava, Slovakia.
The human pineal gland is the largest producer of the hormone melatonin. Pineal acervuli (brain sand), calcified concretions in the pineal gland, have long been studied because of their association with ageing, melatonin production, and neurological disorders. The solid inorganic matter of the hydroxyapatite crystals often renders sample sectioning impossible, to the extent that the sections lose value.
View Article and Find Full Text PDFEchinostomatids from South African freshwater limpets: phylogenetic analyses and diagnostic morphological features for cercariae of .
J Helminthol
January 2025
University of Johannesburg, Department of Zoology, Auckland Park, 2006, Johannesburg, South Africa.
Species of the family Echinostomatidae use diverse gastropod taxa as first intermediate hosts. However, identification of echinostomatid larvae often proves difficult because of incomplete information on their life cycles and lack of molecular data that can link larvae to the corresponding known adults. Here, echinostomatids that were isolated from freshwater limpets in South Africa were described using light and scanning electron microscopy, and ribosomal (28S, ITS, and 18S) and mitochondrial () DNA sequences.
View Article and Find Full Text PDFS100-positive stroma in salivary gland basal cell adenomas: a neoplastic component with CTNNB1 mutations.
Virchows Arch
December 2024
Division of Translational Oncoimmunology, Aichi Cancer Center Research Institute, Nagoya, Japan.
Basal cell adenomas (BCAs) are benign epithelial tumors of the salivary gland, characterized by the proliferation of basaloid and luminal cells. In addition, a distinctive spindle cell stroma, that is immunohistochemically-positive for S100, is often observed in BCAs. Based on the ultrastructural findings, the S100-positive stroma was presumed to originate from neoplastic myoepithelial cells.
View Article and Find Full Text PDFA Histomorphologic and Ultrastructural Report of an Oncocytic Adrenal Cortical Carcinoma With Clinicoradiologic Correlates.
Cureus
November 2024
Department of Pathology and Laboratory Medicine, National Kidney and Transplant Institute, Quezon City, PHL.
Oncocytic adrenal cortical carcinoma (ACC) is a rare malignant adrenal cortical tumor with limited documented case reports. Herein, a 65-year-old female patient presented with a large, solid adrenal mass. A diagnosis of oncocytic ACC was rendered with the following tumor characteristics: The tumor entirely consists of diffuse sheets of polygonal cells with bizarre nuclear atypia and deeply eosinophilic cytoplasm.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!