AI Article Synopsis
- The study assessed the prevalence of delayed gastric emptying in patients with functional dyspepsia, finding that 23% had delays for solids and 35% for liquids.
- Factors such as vomiting and postprandial fullness were linked to delayed solid emptying, while postprandial fullness and severe early satiety were associated with delayed liquid emptying.
- The findings suggest that certain dyspeptic patients experience delayed gastric emptying, particularly related to specific symptoms like fullness and vomiting.
Article Abstract
Objective: The relationship between functional dyspepsia and delayed gastric emptying of solids or liquids is still unclear. The aim of the present study was to investigate in dyspeptic patients the prevalence of delayed gastric emptying for solids or for liquids and to investigate the relationship to the dyspepsia symptom pattern.
Methods: In 392 and 330 patients with functional dyspepsia, the solid and liquid gastric emptying, respectively, was measured using breath tests, and the severity of eight dyspeptic symptoms was scored.
Results: Gastric emptying of solids and liquids were delayed in 23% and 35% of the patients. Multivariate analysis showed that the presence of vomiting and postprandial fullness was associated with delayed solid emptying (OR 2.65, 95% CI = 1.62-4.35 and OR 3.08, 95% CI = 1.28-9.16, respectively). Postprandial fullness was also associated with the risk of delayed liquid emptying when symptom was present (OR 3.5, 95% CI = 1.57-8.68), relevant or severe (OR 2.504, 95% CI = 1.41-4.65), and severe (OR 2.214, 95% CI = 1.34-3.67). Severe early satiety was associated with the risk of delayed liquid emptying (OR 1.902, 95% CI = 1.90-3.30).
Conclusions: A subset of dyspeptic patients has delayed gastric emptying of solids or of liquids. Delayed gastric emptying of solids was constantly associated with postprandial fullness and with vomiting. Delayed emptying for liquids was also associated with postprandial fullness and with severe early satiety.
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| http://dx.doi.org/10.1111/j.1572-0241.2003.07389.x | DOI Listing |
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