The effectiveness of galactomannan detection with the Platelia test was evaluated in a prospective study of 3,327 sera from 807 patients. The specificity was 99.6% (748 of 751 cases). For the groups of patients with proven and probable invasive aspergillosis, the sensitivity was 50.0% (17 of 34 cases). The disappointing sensitivity associated with the presence of rare false-positive cases underlines the limits of this test.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC154675PMC
http://dx.doi.org/10.1128/JCM.41.5.2184-2186.2003DOI Listing

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