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Association of digital eye strain with central corneal thickness: a cross-sectional observational pilot study.
Int Ophthalmol
January 2025
Department of Ophthalmology, Command Hospital, Pune, 411040, India.
Purpose: This study aimed to evaluate whether the digital eye strain (DES) was associated with the low central corneal thickness (CCT).
Methods: This observational cross-sectional pilot study was conducted from April 2023 to October 2023 at a tertiary eye care centre in North India, where CCT values were compared between subjects with DES and those without DES. Two hundred and eighty subjects (n = 280) aged 15-40 years with clear corneas and lenses were initially included in this study.
Bibliometric analysis of published works in ocular trauma: a growing focus on open globe injury.
Int Ophthalmol
January 2025
Department of Ophthalmology, Rutgers New Jersey Medical School, Institute of Ophthalmology and Visual Science, Newark, NJ, USA.
Purpose: The purpose of this study is to analyze the trends and characteristics of ocular trauma research published from 2000 to 2022 to delineate the trajectory of the field's research, provide information about the network of key contributors, and help determine future research strategies and direction.
Methods: Web of Science was queried for published works using a series of keywords relating to ocular trauma: "globe rupture", "ruptured globe", "globe injury", "ocular trauma", "intraocular foreign body", "eye trauma", "eye injury", and "traumatic endophthalmitis". All article information was compiled using the VOSviewer software.
Thermal ocular burns and evaluation of associated limbal stem cell deficiency in the light of global consensus.
Int Ophthalmol
January 2025
Department of Ophthalmology, Ege University Faculty of Medicine, 35100, Bornova, Izmir, Türkiye.
Purpose: The aim of the present study is to examine the demographic data and clinical features of ocular surface injuries due to thermal burns and to evaluate LSCD in the light of global consensus.
Methods: Thirty-three eyes of 20 cases with ocular surface injury due to thermal burn who attended to the clinic between 2012 and 2023 were included in the study. LSCD severity was staged according to the global consensus which was published in 2019.
Improving the diagnostic accuracy of referrals for papilloedema (DIPP) study: protocol for a mixed-methods study.
BMJ Open
January 2025
Bristol Eye Hospital, University Hospitals Bristol & Weston NHS Foundation Trust, Bristol, UK.
Introduction: Papilloedema can be the first sign of life-threatening disease, for example, brain tumours. Due to the potential seriousness of this clinical sign, the detection of papilloedema would normally prompt urgent hospital referral for further investigation. The problem is that many benign structural variations of optic nerve anatomy can be mistaken for papilloedema, so-called pseudopapilloedema.
View Article and Find Full Text PDFCiliopathy-associated missense mutations in IFT140 are tolerated by the inherent resilience of the IFT machinery.
Mol Cell Proteomics
January 2025
Institute for Ophthalmic Research, Center for Ophthalmology, University of Tübingen, Elfriede-Aulhorn-Strasse 7, 72076 Tübingen, Germany. Electronic address:
Genotype-phenotype correlations of rare diseases are complicated by low patient number, high phenotype variability and compound heterozygosity. Mutations may cause instability of single proteins, and affect protein complex formation or overall robustness of a specific process in a given cell. Ciliopathies offer an interesting case for studying genotype-phenotype correlations as they have a spectrum of severity and include diverse phenotypes depending on different mutations in the same protein.
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