The scanning electronmicroscopic appearances of hypertrophic and keloid scar before and after treatment, mature scar and normal skin have been investigated. There is a graduation of features such as collagen orientation and fibre size which accompanies the clinical maturation from the active hypertrophic state into mature scar, a process which is hastened but not materially altered by treatment with steroid or compression-occlusion.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2496174PMC
http://dx.doi.org/10.1136/pgmj.52.606.219DOI Listing

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