AI Article Synopsis
- This study explores the factors influencing parental consent for pediatric clinical trials, focusing on motivations behind participation.
- The main reasons parents consented included a desire to gain knowledge about their child's illness and contribute to medical research, while free medication was more significant for families with lower income.
- The findings highlight the need for researchers to consider ethical aspects and incentives that attract parents to enroll their children in clinical studies.
Article Abstract
Background: Although previous studies have looked at the motivation behind enrollment in clinical trials of adults and healthy subjects, little is known about the factors influencing parental consent in pediatric clinical studies where the subjects themselves do not provide consent.
Objective: This study was conducted to define a group of factors that impact parental consent in the pediatric clinical trial. This may allow investigators to identify a subset of specific appealing aspects of clinical trials that will promote participation while also bringing ethical issues to light that may require further consideration.
Methods: Forty-four parents or guardians of children currently participating in clinical asthma research completed questionnaires from July 1999 to September 1999 pertaining to motives for allowing their child to participate in clinical trials. The responses were then rated on a Likert numerical scale.
Results: The most important motive for parents is learning more about their child's illness. Next important was the motive of helping medical knowledge. Availability of free medication was negatively correlated with family income.
Conclusions: Although altruistic motives are present in pediatric asthma research, most parents/guardians gave consent for their child to learn more about their child's asthma. Access to free medication was more important in families with lower incomes than in families with higher incomes.
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| http://dx.doi.org/10.1542/peds.111.5.1037 | DOI Listing |
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