Objective: To determine which patient beliefs associated with influenza vaccination changed during a vaccine shortage year (2000-2001) from a nonshortage year (1999-2000).
Methods: Elderly patients (n=319), who had been previously interviewed about the 1999-2000 influenza season, were interviewed regarding the 2000-2001 season. Participants were from inner-city and suburban medical practices receiving influenza vaccine supply on time or late in the season.
Results: Although vaccination rates did not diminish due to the influenza vaccine shortage (73% in 1999-2000 vs 74% in 2000-2001), some patient attitudes changed. More respondents expressed concerns about the influenza vaccine (3% in 1999-2000 vs 12% in 2000-2001, p<0.0001), and fewer responded that friends thought that they should get the vaccine (75% 1999-2000 vs 66% 2000-2001, p=0.005); that if one person in the household "got the flu" others would also (71% 1999-2000 vs 67% 2000-2001, p<0.0001), and that "a person who does not get the flu shot will get influenza" (36% 1999-2000 vs 30% 2000-2001, p=0.02).
Conclusions: The influenza vaccine shortage resulted in a small increase in concerns about influenza vaccine, even in a population with good access to vaccine and high vaccination rates. Vaccine availability updates should include reassurances of vaccine safety and efficacy.
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http://dx.doi.org/10.1016/s0749-3797(03)00018-7 | DOI Listing |
Clin Microbiol Infect
January 2025
Amiens, France. Electronic address:
Mol Ther
January 2025
Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:
Vet Microbiol
January 2025
College of Veterinary Medicine, Jilin Provincial Engineering Research Center of Animal Probiotics, Jilin Provincial Key Laboratory of Animal Microecology and Healthy Breeding, Engineering Research Center of Microecological Vaccines (Drugs) for Major Animal Diseases, Ministry of Education, Jilin Agricultural University, Changchun 130118, China. Electronic address:
Swine influenza virus invades the host through the respiratory mucosa, which severely restricts the development of the pig breeding industry. To construct monomeric and trimeric vaccines, we developed recombinant Escherichia coli Nissle 1917 (EcN) strains that express the receptor binding site (RBS) of the hemagglutinin (HA) antigen from H1N1 swine influenza virus. After the mucosal immunization of mice, we found that probiotics activated CD40 and CD86 in DCs and increased the levels of IL-4 and IFN-γ secretion by T cells.
View Article and Find Full Text PDFMedicina (Kaunas)
January 2025
Department of Health Sciences, University of Genoa, 16132 Genoa, Italy.
: Three respiratory syncytial virus (RSV) vaccines have been recently made available for older adults. Understanding the principal characteristics of the first vaccine-takers can pave the way for a successful vaccination campaign. The objective of this study was to explore the sociodemographic and clinical characteristics of the first Italian users of an adjuvanted RSV vaccine and their attitudes towards RSV and vaccination.
View Article and Find Full Text PDFInt J Environ Res Public Health
January 2025
Programme for Emerging Infections, Infectious Disease Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Mohakhali, Dhaka 1212, Bangladesh.
Background: Influenza remains a significant public health challenge in low- and middle-income countries (LMICs) like Bangladesh, where vaccine uptake remains low despite the substantial disease burden. Physicians play a vital role in promoting vaccination, yet their intentions and influencing factors are not well understood.
Methods: We conducted a cross-sectional study from June to October 2022 across four tertiary-level hospitals in Bangladesh using a questionnaire grounded in the Theory of Planned Behavior (TPB).
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