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Isolated central nervous system relapse in blast crisis of chronic myeloid leukemia: a case report.
J Yeungnam Med Sci
December 2024
Haematology Unit, Department of Pathology, Hospital Sultanah Aminah, Ministry of Health, Malaysia.
Chronic myeloid leukemia (CML) typically progresses from a chronic phase to an accelerated phase, and eventually to a blast crisis, often involving the bone marrow and peripheral blood, if left untreated. Central nervous system (CNS) involvement is an uncommon manifestation of CML, particularly as an isolated CNS relapse. Here, we present a rare case of CML in lymphoid blast crisis with an isolated CNS relapse.
View Article and Find Full Text PDFTalaromyces marneffei central nervous system infection unveiled by the novel Mp1p antigen detection assay in AIDS patient.
BMC Infect Dis
December 2024
Central Laboratory, Chongqing Public Health Medical Centre, Chongqing, China.
Background: In acquired immunodeficiency syndrome patients, Talaromyces marneffei infections are mostly disseminated and may involve the skin, mucosa, respiratory system, digestive system, lymphatic system, and as some reports indicate, the nervous system. Mp1p, a cell wall-specific polysaccharide in Talaromyces marneffei, is used for laboratory diagnosis of Talaromyces marneffei in blood and urine samples. However, Cerebrospinal fluid Mp1p diagnosis of Talaromyces marneffei central nervous system infection has not been reported.
View Article and Find Full Text PDFMolecular epidemiology and distribution of in human immunodeficiency-positive patients in China.
J Int Med Res
December 2024
Department of Dermatology, Shanghai Fourth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Objective: This study aims to inform the prevention and treatment of infections in China by analyzing the molecular epidemiology and distribution patterns of the pathogen.
Methods: A cross-sectional study was conducted involving a retrospective analysis of 64 clinical strains of isolated from January 2018 to April 2023 across various domestic regions. Patient information was collected from human immunodeficiency virus-positive individuals in multiple hospitals located in 19 cities within China's southeastern coastal and southwestern regions.
Antibiotic susceptibility and phenotypic profile of species isolated from different clinical samples from health facilities: A cross-sectional study.
SAGE Open Med
December 2024
Branch of Clinical Sciences, College of Medicine, University of Sulaimani, Sulaimaniyah, Iraq.
Background: species are widely distributed in nature and found in various human body sites.
Objectives: To determine the antibiotic susceptibility pattern of species isolated from different clinical samples.
Methods: This cross-sectional study was conducted on 400 clinical specimens from conveniently sampled patients seeking healthcare at two health facilities in sulaimani / Iraq.
Fungal positivity and other laboratory parameters in HIV- and non-HIV-related cryptococcal meningitis patients upon antifungal treatment.
APMIS
January 2025
Mindray North America, Mahwah, New Jersey, USA.
The association between fungal positivity in cerebral spinal fluid (CSF) and other laboratory parameters in cryptococcal meningitis (CM) with or without HIV infection is unclear. India ink staining and culture were used to detect the Cryptococcus in the CSF during the treatment course. Hematology analysis and chemistry analysis of CSF were also performed.
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