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The effects of TECAR therapy on pain, range of motion, strength and subscale of HAGOS questionnaire in athletes with chronic adductor related groin pain: a randomized controlled trial.
BMC Musculoskelet Disord
January 2025
Department of Physiotherapy, Iranian Center of Excellence in Physiotherapy, Rehabilitation Research Center, School of Rehabilitation Sciences, Iran University of Medical Sciences, Madadkaran All., Shahnazari St., Madar Sq., Mirdamad Blvd., Tehran, Iran.
Introduction: Groin pain is a common issue among athletes. Adductor-related pain is known as the most common cause of groin pain. Although, non-operative treatments have limited efficacy, Capacitive and Resistive Energy Transfer (TECAR), can be used in the treatment of musculoskeletal conditions.
View Article and Find Full Text PDFImpact of Smovey Vibration Versus Dumbbell Resistance on Muscle Activation in Women.
Med Sci Monit
January 2025
Department of Sports Rehabilitation, Kyungpook National University, Sangju, South Korea.
BACKGROUND The Smovey Vibroswing exercise device consists of a circular tube containing 4 steel balls, partly covered by a cushioning handle, to strengthen the arm and shoulder muscles. This study aimed to compare the effects of using a Smovey Vibroswing versus dumbbell exercises on muscle activity and body composition of the upper limbs in 23 women under 30 years of age. MATERIAL AND METHODS Subjects were 23 women under the age of 30 years, residing in South Korea, with no musculoskeletal diseases or shoulder surgeries in the past year.
View Article and Find Full Text PDFPromoted read-through and mutation against pseudouridine-CMC by an evolved reverse transcriptase.
Commun Biol
January 2025
Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, MA, USA.
Pseudouridine (Ψ) is an abundant RNA chemical modification that plays critical biological functions. Current Ψ detection methods are limited in identifying Ψs at base-resolution in U-rich sequence contexts, where Ψ occurs frequently. Here we report "Mut-Ψ-seq" that utilizes the classic N-cyclohexyl N'-(2-morpholinoethyl)carbodiimide (CMC) agent and an evolved reverse transcriptase ("RT-1306") for Ψ mapping at base-resolution.
View Article and Find Full Text PDFDiscovery of novel tris-1,2,3-triazole-based hybrids as VEGFR2 inhibitors with potent anti-proliferative and cytotoxicity through apoptosis induction.
Bioorg Chem
February 2025
Department of Chemistry, Faculty of Science, Taibah University, Al-Madinah Al-Munawarah 30002 Saudi Arabia. Electronic address:
The discovery of novel anti-cancer drugs motivated us to synthesize a new series of triple 1,2,3-triazole-based arm scaffolds featuring distinct un functionalized alkyl and/or aryl side chains with possible anti-cancer action using the click chemistry approach under both conventional and green microwave irradiation (MWI) methods. The Cu(I) catalyzed cycloaddition reaction of targeted tris-alkyne with un functionalized aliphatic and aromatic azides has been adopted as an efficient approach for synthesizing the desired click adducts. Microwave irradiation improved the synthetic processes, resulting in higher yields and faster reaction times.
View Article and Find Full Text PDFSystematic Evaluation of IMU Sensors for Application in Smart Glove System for Remote Monitoring of Hand Differences.
Sensors (Basel)
December 2024
Engineering for Health Research Centre, Aston University, Aston Triangle, Birmingham B4 7ET, UK.
Human hands have over 20 degrees of freedom, enabled by a complex system of bones, muscles, and joints. Hand differences can significantly impair dexterity and independence in daily activities. Accurate assessment of hand function, particularly digit movement, is vital for effective intervention and rehabilitation.
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