Summary: MARAN is a web-based application for normalizing microarray data. MARAN comprises a generic ANOVA model, an option for Loess fitting prior to ANOVA analysis, and a module for selecting genes with significantly changing expression.
Availability: http://www.esat.kuleuven.ac.be/maran/.
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http://dx.doi.org/10.1093/bioinformatics/btg085 | DOI Listing |
Clin Exp Dermatol
November 2024
Faculdade de Medicina de Botucatu, UNESP Medical School, Botucatu, SP, Brazil.
Background: Trials evaluating the effectiveness of topical treatments for actinic cheilitis (AC) are scarce. Despite no comparative data, phenol-croton peeling has been reported as effective in treating this condition.
Methods: An open, randomized trial was conducted to compare the effectiveness and tolerability of 1.
Curr Issues Mol Biol
September 2024
College of Life Sciences, China West Normal University, Nanchong 637009, China.
To explore the mitogenome characteristics of Tetratomidae and the phylogenetic position of this family in Tenebrionoidea, the mitogenome of Mařan, 1940 was sequenced, annotated, and analyzed. The mitogenome is consistent with Tenebrionoidea species in gene length, genomic organization, codon usage, and secondary structures of transfer genes (tRNAs). Most protein-coding genes (PCGs) originate with a typical ATN start codon, except and which start with TTG.
View Article and Find Full Text PDFJ Cell Mol Med
October 2024
Department of Hepatic Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Hepatocellular carcinoma (HCC) stands as the most prevalent and treatment-resistant malignant tumour, characterized by a dismal prognosis. Croton acylation (CA) has recently gained attention as a critical factor in cancer pathogenesis. This study sought to rapidly identify prognostic features of HCC linked to CA.
View Article and Find Full Text PDFMolecules
September 2024
Institute of Chemical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Sangre de drago, the sap of Müll. Arg. tree, has been used for centuries in traditional medicine owing to its diverse biological activities.
View Article and Find Full Text PDFCancers (Basel)
August 2024
Radiation Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, 50134 Florence, Italy.
: The main goal of radiotherapy (RT) is to deliver a precise dose to the target while sparing the surrounding normal tissue and minimizing side effects. Appropriate patient immobilization is crucial, especially for head and neck cancer (HNC) and Brain Cancer (BC). Conventional closed-face masks (CFMs), while effective in minimizing head motion, can cause significant discomfort, anxiety, and claustrophobia.
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