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Human beings display laterilised behaviour. In sport, including golf, players adopt a right- or left-handed stance. There may be advantages in going against convention in the position of the dominant hand relative to golf stance.
View Article and Find Full Text PDFNeutralizing antibody landscape of the non-polio Enteroviruses and future strategy.
Front Immunol
January 2025
Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China.
The non-polio Enteroviruses (NPEVs), consist of enteroviruses, coxsackieviruses, echoviruses, and rhinoviruses, are causative agents for a wide variety of diseases, ranging from common cold to encephalitis and acute flaccid paralysis (AFP). In recent years, several NPEVs have become serious public health threats, include EV-A71, which has caused epidemics of hand-foot-and-mouth disease (HMFD) in Southeast Asia, and EV-D68, which caused outbreaks of severe respiratory disease in children worldwide. Infections with these viruses are associated with neurological diseases like aseptic meningitis and AFP.
View Article and Find Full Text PDFHand, foot and mouth disease (HFMD) is a major public health issue in Hubei Province; however, research on the direct and indirect effects of factors affecting HFMD is limited. This study employed structural equation modeling (SEM) and geographically weighted regression (GWR) to investigate the various impacts and spatial variations in the factors influencing the HFMD epidemic in Hubei Province from 2016 to 2018. The results indicated that (1) with respect to the direct effects, the number of primary school students had the greatest positive direct effect on the number of HFMD cases, with a coefficient of 0.
View Article and Find Full Text PDFA serosurvey study of hand, foot and mouth disease in healthy children aged 6 to 71 months old in West Bandung and Bandung Region, Indonesia.
BMC Infect Dis
January 2025
Public Health Department, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.
Background: Hand, foot, and mouth disease (HFMD) is an infectious disease that often affects children under 5 years of age. Over the past 20 years, enterovirus 71 (EV71) has become a major concern among children, especially in the Asia-Pacific region. Currently, there are no data showing the seroprevalence of HMFDs in Indonesia.
View Article and Find Full Text PDFIncreased TSPO alleviates neuropathic pain by preventing pyroptosis via the AMPK-PGC-1α pathway.
J Headache Pain
January 2025
Department of Hand and Foot Surgery, China-Japan Union Hospital of Jilin University, Changchun, China.
Neuropathic pain poses a significant clinical challenge, largely due to the incomplete understanding of its molecular mechanisms, particularly the role of mitochondrial dysfunction. Bioinformatics analysis revealed that pyroptosis and inflammatory responses induced by spared nerve injury (SNI) in the spinal dorsal horn play a critical role in the initiation and persistence of neuropathic pain. Among the factors involved, TSPO (translocator protein) emerged as a key regulator.
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