AI Article Synopsis
- Milk thistle contains beneficial compounds that help protect the liver and silymarin is one of these compounds.
- The study investigated how different temperatures (50, 70, 85, and 100 degrees C) affect the extraction of silymarin from milk thistle seed meal over a 210-minute period.
- Results showed that extracting at 100 degrees C produced higher yields of certain compounds like taxifolin and silychristin compared to traditional ethanol extraction methods, indicating that temperature plays a significant role in optimizing yields for specific compounds.
Article Abstract
Milk thistle contains compounds that display hepatoxic protection properties. We examined the batch extraction of silymarin compounds from milk thistle seed meal in 50, 70, 85, and 100 degrees C water as a function of time. After 210 min of extraction at 100 degrees C, the yield of taxifolin was 1.2 mg/g of seed, a 6.2-fold increase over the results obtained in a Soxhlet extraction with ethanol on pretreated (defatted) seeds. Similarly, the yield of silychristin was 5.0 mg/g of seed, a 3.8-fold increase. The yields of silybinin A and silybinin B were 1.8 and 3.3 mg/g of seed, respectively, or roughly 30% of the Soxhlet yield. The ratios of the extracted compounds, and particularly the ratios at long extraction times, showed that the more polar compounds (taxifolin and silychristin) were preferentially extracted at 85 degrees C, while the less polar silybinin was favored at 100 degrees C.
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| http://dx.doi.org/10.1385/abab:108:1-3:881 | DOI Listing |
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