Nogo-A, a reticulon protein expressed by oligodendrocytes, contributes to the axonal growth inhibitory action of central myelin in growth cone collapse and neurite outgrowth in vitro assays, and antibody and inhibitor studies have implicated a role for Nogo in regeneration in the adult CNS in vivo. Three independent labs have now produced Nogo knockout mice with, quite unexpectedly, three different regeneration phenotypes.
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http://dx.doi.org/10.1016/s0896-6273(03)00233-2 | DOI Listing |
Sci Rep
January 2025
School of Physical Education & Health, Shanghai University of International Business and Economics, Shanghai, China.
This study aims to examine the relationship between physical activity and inhibitory function in college students with depressive symptoms and to explore the role of resting EEG as a mediator in this relationship. Specifically, it analyzes how physical activity correlates with inhibitory function and identifies potential routes through which physical activity impacts inhibitory function. A cross-sectional study was conducted involving 154 college students with depressive symptoms.
View Article and Find Full Text PDFHum Brain Mapp
February 2025
Department of Psychological and Brain Sciences, University of Delaware, Newark, Delaware, USA.
Converging lines of research indicate that inhibitory control is likely to be compromised in contexts that place competing demands on emotional, motivational, and cognitive systems, potentially leading to damaging impulsive behavior. The objective of this study was to identify the neural impact of three challenging contexts that typically compromise self-regulation and weaken impulse control. Participants included 66 healthy adults (M/SD = 29.
View Article and Find Full Text PDFBrain Sci
January 2025
Department of Physical Education, Shanghai Jiao Tong University, Shanghai 200240, China.
: Obesity presents a significant global public health challenge and is associated with declines in both general and food-related inhibitory control, crucial for maintaining a healthy weight and preventing obesity progression. An increasing body of research suggests that acute aerobic exercise may improve inhibitory function. However, the effects and underlying mechanisms of acute aerobic exercise on both general and food-related inhibition in obese adults remain unclear.
View Article and Find Full Text PDFBr J Psychiatry
January 2025
Key Laboratory of Cognition and Personality, Ministry of Education, Faculty of Psychology, Southwest University, Chongqing, China.
Background: Knowledge is growing on the essential role of neural circuits involved in aberrant cognitive control and reward sensitivity for the onset and maintenance of binge eating.
Aims: To investigate how the brain's reward (bottom-up) and inhibition control (top-down) systems potentially and dynamically interact to contribute to subclinical binge eating.
Method: Functional magnetic resonance imaging data were acquired from 30 binge eaters and 29 controls while participants performed a food reward Go/NoGo task.
Biomed Phys Eng Express
January 2025
F. Joseph Halcomb III, MD, Department of Biomedical Engineering, University of Kentucky, 143 Graham Ave., Lexington, Kentucky, 40506, UNITED STATES.
Brain-computer interfaces (BCIs) offer disabled individuals the means to interact with devices by decoding the electroencephalogram (EEG). However, decoding intent in fine motor tasks can be challenging, especially in stroke survivors with cortical lesions. Here, we attempt to decode graded finger extension from the EEG in stroke patients with left-hand paresis and healthy controls.
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